CR021_MOUSE
ID CR021_MOUSE Reviewed; 217 AA.
AC Q5XFZ0; Q9CXC1; Q9CZ41;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-MAR-2007, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=UPF0711 protein C18orf21 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Lung;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Czech II; TISSUE=Jaw, and Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the UPF0711 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB28609.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AK013030; BAB28609.1; ALT_FRAME; mRNA.
DR EMBL; AK018391; BAB31191.1; -; mRNA.
DR EMBL; BC037075; AAH37075.1; -; mRNA.
DR EMBL; BC084681; AAH84681.1; -; mRNA.
DR CCDS; CCDS29101.1; -.
DR RefSeq; NP_080805.1; NM_026529.4.
DR AlphaFoldDB; Q5XFZ0; -.
DR STRING; 10090.ENSMUSP00000095251; -.
DR iPTMnet; Q5XFZ0; -.
DR PhosphoSitePlus; Q5XFZ0; -.
DR EPD; Q5XFZ0; -.
DR MaxQB; Q5XFZ0; -.
DR PaxDb; Q5XFZ0; -.
DR PeptideAtlas; Q5XFZ0; -.
DR PRIDE; Q5XFZ0; -.
DR Antibodypedia; 54637; 25 antibodies from 11 providers.
DR DNASU; 68046; -.
DR Ensembl; ENSMUST00000097646; ENSMUSP00000095251; ENSMUSG00000024273.
DR GeneID; 68046; -.
DR KEGG; mmu:68046; -.
DR UCSC; uc008egt.1; mouse.
DR MGI; MGI:1915296; 2700062C07Rik.
DR VEuPathDB; HostDB:ENSMUSG00000024273; -.
DR eggNOG; ENOG502S2A1; Eukaryota.
DR GeneTree; ENSGT00390000013383; -.
DR HOGENOM; CLU_110760_0_0_1; -.
DR InParanoid; Q5XFZ0; -.
DR OMA; HKGVNRD; -.
DR OrthoDB; 1377101at2759; -.
DR PhylomeDB; Q5XFZ0; -.
DR TreeFam; TF330815; -.
DR BioGRID-ORCS; 68046; 11 hits in 74 CRISPR screens.
DR PRO; PR:Q5XFZ0; -.
DR Proteomes; UP000000589; Chromosome 18.
DR RNAct; Q5XFZ0; protein.
DR Bgee; ENSMUSG00000024273; Expressed in secondary oocyte and 63 other tissues.
DR ExpressionAtlas; Q5XFZ0; baseline and differential.
DR Genevisible; Q5XFZ0; MM.
DR InterPro; IPR029779; DUF4674.
DR PANTHER; PTHR31402; PTHR31402; 1.
DR Pfam; PF15719; DUF4674; 1.
PE 2: Evidence at transcript level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..217
FT /note="UPF0711 protein C18orf21 homolog"
FT /id="PRO_0000279449"
FT REGION 131..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 126
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q32NC0"
FT MOD_RES 130
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q32NC0"
FT MOD_RES 139
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q32NC0"
FT CONFLICT 205
FT /note="N -> Y (in Ref. 2; AAH84681)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 217 AA; 24123 MW; C2BA8D98B6ABCD78 CRC64;
MRQKYYIEAA ARGLVGSCPG QARYLLWAYS STHEDNSTFQ ETCPHCFQLL VLDNSRVRLK
PKAKLTPKIQ KLLNREARND TLSFKEAKLL RKYKDSTSVL LITCRTCNRT VRHHGKSRSF
LWALKSNAAT AANKASPKTP KRTAPGSANL GQSTNGSKGK SPSLTIRTPT SGQSTPICSS
RNGSKRKKHF SQLKALLSQS ASDKNPKLDF RHFLSSL
