CR032_BOVIN
ID CR032_BOVIN Reviewed; 76 AA.
AC Q3ZC78;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=UPF0729 protein C18orf32 homolog;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May activate the NF-kappa-B signaling pathway.
CC {ECO:0000250|UniProtKB:Q8TCD1}.
CC -!- SUBUNIT: Interacts with DERL1 and AMFR. {ECO:0000250|UniProtKB:Q8TCD1}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000250|UniProtKB:Q8TCD1}. Lipid droplet
CC {ECO:0000250|UniProtKB:Q8TCD1}.
CC -!- PTM: Undergoes ER-associated degradation (ERAD).
CC {ECO:0000250|UniProtKB:Q8TCD1}.
CC -!- SIMILARITY: Belongs to the UPF0729 family. {ECO:0000305}.
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DR EMBL; BC102856; AAI02857.1; -; mRNA.
DR RefSeq; NP_001181991.1; NM_001195062.1.
DR RefSeq; XP_010817241.1; XM_010818939.2.
DR RefSeq; XP_010817242.1; XM_010818940.2.
DR RefSeq; XP_010817243.1; XM_010818941.2.
DR AlphaFoldDB; Q3ZC78; -.
DR STRING; 9913.ENSBTAP00000028439; -.
DR PaxDb; Q3ZC78; -.
DR PRIDE; Q3ZC78; -.
DR Ensembl; ENSBTAT00000028439; ENSBTAP00000028439; ENSBTAG00000021334.
DR GeneID; 767921; -.
DR KEGG; bta:767921; -.
DR CTD; 767921; -.
DR VEuPathDB; HostDB:ENSBTAG00000021334; -.
DR VGNC; VGNC:52682; C24H18orf32.
DR eggNOG; ENOG502S738; Eukaryota.
DR GeneTree; ENSGT00390000018741; -.
DR HOGENOM; CLU_191635_0_0_1; -.
DR InParanoid; Q3ZC78; -.
DR OMA; KVDCKGT; -.
DR OrthoDB; 1627271at2759; -.
DR TreeFam; TF324662; -.
DR Proteomes; UP000009136; Chromosome 24.
DR Bgee; ENSBTAG00000021334; Expressed in oocyte and 105 other tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
DR GO; GO:0005811; C:lipid droplet; ISS:UniProtKB.
DR InterPro; IPR026776; UPF0729.
DR PANTHER; PTHR13456; PTHR13456; 1.
DR Pfam; PF14975; DUF4512; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Lipid droplet; Reference proteome.
FT CHAIN 1..76
FT /note="UPF0729 protein C18orf32 homolog"
FT /id="PRO_0000321907"
FT REGION 1..37
FT /note="Necessary for its localzation to the endoplasmic
FT reticulum and lipid droplets"
FT /evidence="ECO:0000250|UniProtKB:Q8TCD1"
FT REGION 47..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 76 AA; 8830 MW; C6020885B24E4552 CRC64;
MVCIPCIVIP VLLWVYKKFL EPYIYPLISP FVSRMWPRKA IRETNDKNKG KVDYKGADIN
GLPTRGPTEM CDKKKD