ID   CR032_PONAB             Reviewed;          76 AA.
AC   Q5R7A0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=UPF0729 protein C18orf32 homolog;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May activate the NF-kappa-B signaling pathway.
CC       {ECO:0000250|UniProtKB:Q8TCD1}.
CC   -!- SUBUNIT: Interacts with DERL1 and AMFR. {ECO:0000250|UniProtKB:Q8TCD1}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q8TCD1}. Lipid droplet
CC       {ECO:0000250|UniProtKB:Q8TCD1}.
CC   -!- PTM: Undergoes ER-associated degradation (ERAD).
CC       {ECO:0000250|UniProtKB:Q8TCD1}.
CC   -!- SIMILARITY: Belongs to the UPF0729 family. {ECO:0000305}.
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DR   EMBL; CR860218; CAH92360.1; -; mRNA.
DR   AlphaFoldDB; Q5R7A0; -.
DR   STRING; 9601.ENSPPYP00000010280; -.
DR   eggNOG; ENOG502S738; Eukaryota.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
DR   GO; GO:0005811; C:lipid droplet; ISS:UniProtKB.
DR   InterPro; IPR026776; UPF0729.
DR   PANTHER; PTHR13456; PTHR13456; 1.
DR   Pfam; PF14975; DUF4512; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Lipid droplet; Reference proteome.
FT   CHAIN           1..76
FT                   /note="UPF0729 protein C18orf32 homolog"
FT                   /id="PRO_0000321910"
FT   REGION          1..37
FT                   /note="Necessary for its localzation to the endoplasmic
FT                   reticulum and lipid droplets"
FT                   /evidence="ECO:0000250|UniProtKB:Q8TCD1"
FT   REGION          45..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   76 AA;  8611 MW;  C13DBA022484ABE5 CRC64;
     MVCIPCIVIP VLLWIYKKFL EPYIYPLVSP FVSRIWPKKA IQESNDTNKG KVDCKGADMN
     GLPTKGPTEI SDKKED