CR15A_ARATH
ID CR15A_ARATH Reviewed; 139 AA.
AC Q42512; F4IP48;
DT 01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Protein COLD-REGULATED 15A, chloroplastic {ECO:0000303|PubMed:16668917};
DE Short=AtCOR15A {ECO:0000303|PubMed:16668917};
DE Flags: Precursor;
GN Name=COR15A {ECO:0000303|PubMed:16668917};
GN OrderedLocusNames=At2g42540 {ECO:0000312|Araport:AT2G42540};
GN ORFNames=F14N22.19 {ECO:0000312|EMBL:AAD22999.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAB87705.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), MISCELLANEOUS, SUBCELLULAR
RP LOCATION, TRANSIT PEPTIDE, AND INDUCTION BY COLD.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta; TISSUE=Rosette leaf;
RX PubMed=16668917; DOI=10.1104/pp.99.2.519;
RA Lin C., Thomashow M.F.;
RT "DNA sequence analysis of a complementary DNA for cold-regulated
RT Arabidopsis gene cor15 and characterization of the COR 15 polypeptide.";
RL Plant Physiol. 99:519-525(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND INDUCTION BY COLD; DROUGHT AND
RP ABA.
RX PubMed=8193295; DOI=10.1007/bf00029852;
RA Baker S.S., Wilhelm K.S., Thomashow M.F.;
RT "The 5'-region of Arabidopsis thaliana cor15a has cis-acting elements that
RT confer cold-, drought- and ABA-regulated gene expression.";
RL Plant Mol. Biol. 24:701-713(1994).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP FUNCTION.
RC STRAIN=cv. Columbia;
RX PubMed=1567390; DOI=10.1016/s0006-291x(05)80304-3;
RA Lin C., Thomashow M.F.;
RT "A cold-regulated Arabidopsis gene encodes a polypeptide having potent
RT cryoprotective activity.";
RL Biochem. Biophys. Res. Commun. 183:1103-1108(1992).
RN [7]
RP SUBCELLULAR LOCATION, AND TRANSIT PEPTIDE.
RX PubMed=8685269; DOI=10.1104/pp.111.1.293;
RA Gilmour S.J., Lin C., Thomashow M.F.;
RT "Purification and properties of Arabidopsis thaliana COR (cold-regulated)
RT gene polypeptides COR15am and COR6.6 expressed in Escherichia coli.";
RL Plant Physiol. 111:293-299(1996).
RN [8]
RP FUNCTION.
RC STRAIN=cv. RLD;
RX PubMed=11038526; DOI=10.1073/pnas.93.23.13404;
RA Artus N.N., Uemura M., Steponkus P.L., Gilmour S.J., Lin C.,
RA Thomashow M.F.;
RT "Constitutive expression of the cold-regulated Arabidopsis thaliana COR15a
RT gene affects both chloroplast and protoplast freezing tolerance.";
RL Proc. Natl. Acad. Sci. U.S.A. 93:13404-13409(1996).
RN [9]
RP INDUCTION BY ABSCISIC ACID; HIGH SALT; POLYETHYLENE GLYCOL AND COLD.
RX PubMed=9668134; DOI=10.2307/3870718;
RA Ishitani M., Xiong L., Lee H., Stevenson B., Zhu J.K.;
RT "HOS1, a genetic locus involved in cold-responsive gene expression in
RT arabidopsis.";
RL Plant Cell 10:1151-1161(1998).
RN [10]
RP FUNCTION.
RC STRAIN=cv. RLD;
RX PubMed=9826741; DOI=10.1073/pnas.95.24.14570;
RA Steponkus P.L., Uemura M., Joseph R.A., Gilmour S.J., Thomashow M.F.;
RT "Mode of action of the COR15a gene on the freezing tolerance of Arabidopsis
RT thaliana.";
RL Proc. Natl. Acad. Sci. U.S.A. 95:14570-14575(1998).
RN [11]
RP INDUCTION BY COLD.
RX PubMed=11706173; DOI=10.1104/pp.010548;
RA Jaglo K.R., Kleff S., Amundsen K.L., Zhang X., Haake V., Zhang J.Z.,
RA Deits T., Thomashow M.F.;
RT "Components of the Arabidopsis C-repeat/dehydration-responsive element
RT binding factor cold-response pathway are conserved in Brassica napus and
RT other plant species.";
RL Plant Physiol. 127:910-917(2001).
RN [12]
RP INDUCTION BY SALT; COLD; ABSCISIC ACID AND POLYETHYLENE GLYCOL.
RX PubMed=11779861; DOI=10.1074/jbc.m109275200;
RA Xiong L., Lee H., Ishitani M., Zhu J.-K.;
RT "Regulation of osmotic stress-responsive gene expression by the LOS6/ABA1
RT locus in Arabidopsis.";
RL J. Biol. Chem. 277:8588-8596(2002).
RN [13]
RP INDUCTION BY COLD; LIGHT AND DROUGHT.
RX PubMed=12148528; DOI=10.1046/j.1365-313x.2002.01249.x;
RA Kim H.-J., Kim Y.-K., Park J.-Y., Kim J.;
RT "Light signalling mediated by phytochrome plays an important role in cold-
RT induced gene expression through the C-repeat/dehydration responsive element
RT (C/DRE) in Arabidopsis thaliana.";
RL Plant J. 29:693-704(2002).
RN [14]
RP INDUCTION BY HIGH LIGHT AND DROUGHT.
RC STRAIN=cv. Columbia;
RX PubMed=12785063; DOI=10.1562/0031-8655(2003)077<0226:ioagrb>2.0.co;2;
RA Kimura M., Yamamoto Y.Y., Seki M., Sakurai T., Sato M., Abe T., Yoshida S.,
RA Manabe K., Shinozaki K., Matsui M.;
RT "Identification of Arabidopsis genes regulated by high light-stress using
RT cDNA microarray.";
RL Photochem. Photobiol. 77:226-233(2003).
RN [15]
RP INDUCTION BY COLD.
RX PubMed=14745450; DOI=10.1038/ng1298;
RA Kim H.-J., Hyun Y., Park J.-Y., Park M.-J., Park M.-K., Kim M.D.,
RA Kim H.-J., Lee M.H., Moon J., Lee I., Kim J.;
RT "A genetic link between cold responses and flowering time through FVE in
RT Arabidopsis thaliana.";
RL Nat. Genet. 36:167-171(2004).
RN [16]
RP INDUCTION BY COLD ACCLIMATION.
RC STRAIN=cv. C24, and cv. Columbia;
RX PubMed=15144380; DOI=10.1111/j.1365-313x.2004.02080.x;
RA Rohde P., Hincha D.K., Heyer A.G.;
RT "Heterosis in the freezing tolerance of crosses between two Arabidopsis
RT thaliana accessions (Columbia-0 and C24) that show differences in non-
RT acclimated and acclimated freezing tolerance.";
RL Plant J. 38:790-799(2004).
RN [17]
RP INDUCTION BY COLD.
RX PubMed=16258011; DOI=10.1104/pp.105.068171;
RA Vergnolle C., Vaultier M.-N., Taconnat L., Renou J.-P., Kader J.-C.,
RA Zachowski A., Ruelland E.;
RT "The cold-induced early activation of phospholipase C and D pathways
RT determines the response of two distinct clusters of genes in Arabidopsis
RT cell suspensions.";
RL Plant Physiol. 139:1217-1233(2005).
RN [18]
RP FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, INDUCTION BY COLD, AND
RP MISCELLANEOUS.
RC STRAIN=cv. Columbia;
RX PubMed=17384167; DOI=10.1104/pp.106.094581;
RA Nakayama K., Okawa K., Kakizaki T., Honma T., Itoh H., Inaba T.;
RT "Arabidopsis Cor15am is a chloroplast stromal protein that has
RT cryoprotective activity and forms oligomers.";
RL Plant Physiol. 144:513-523(2007).
RN [19]
RP FUNCTION.
RX PubMed=18540080; DOI=10.1271/bbb.80214;
RA Nakayama K., Okawa K., Kakizaki T., Inaba T.;
RT "Evaluation of the protective activities of a late embryogenesis abundant
RT (LEA) related protein, Cor15am, during various stresses in vitro.";
RL Biosci. Biotechnol. Biochem. 72:1642-1645(2008).
RN [20]
RP INDUCTION BY COLD.
RX PubMed=19470100; DOI=10.1111/j.1438-8677.2008.00122.x;
RA Lee Y.P., Fleming A.J., Koerner C., Meins F. Jr.;
RT "Differential expression of the CBF pathway and cell cycle-related genes in
RT Arabidopsis accessions in response to chronic low-temperature exposure.";
RL Plant Biol. 11:273-283(2009).
RN [21]
RP INDUCTION BY COLD.
RX PubMed=19500304; DOI=10.1111/j.1365-313x.2009.03938.x;
RA Kwon C.S., Lee D., Choi G., Chung W.I.;
RT "Histone occupancy-dependent and -independent removal of H3K27
RT trimethylation at cold-responsive genes in Arabidopsis.";
RL Plant J. 60:112-121(2009).
RN [22]
RP INDUCTION BY COOLING AND COLD, AND FUNCTION.
RX PubMed=19563440; DOI=10.1111/j.1365-313x.2009.03959.x;
RA Wang Y., Hua J.;
RT "A moderate decrease in temperature induces COR15a expression through the
RT CBF signaling cascade and enhances freezing tolerance.";
RL Plant J. 60:340-349(2009).
RN [23]
RP FUNCTION, MISCELLANEOUS, AND SUBUNIT.
RX PubMed=20510170; DOI=10.1016/j.bbamem.2010.05.015;
RA Thalhammer A., Hundertmark M., Popova A.V., Seckler R., Hincha D.K.;
RT "Interaction of two intrinsically disordered plant stress proteins (COR15A
RT and COR15B) with lipid membranes in the dry state.";
RL Biochim. Biophys. Acta 1798:1812-1820(2010).
RN [24]
RP INVOLVEMENT IN SENESCENCE, AND INDUCTION BY ABSCISIC ACID.
RC STRAIN=cv. Columbia;
RX PubMed=21673078; DOI=10.1105/tpc.111.084913;
RA Yang S.-D., Seo P.J., Yoon H.-K., Park C.-M.;
RT "The Arabidopsis NAC transcription factor VNI2 integrates abscisic acid
RT signals into leaf senescence via the COR/RD genes.";
RL Plant Cell 23:2155-2168(2011).
RN [25]
RP INDUCTION BY SALT.
RX PubMed=21832142; DOI=10.1104/pp.111.179028;
RA Zhang L., Li Z., Quan R., Li G., Wang R., Huang R.;
RT "An AP2 domain-containing gene, ESE1, targeted by the ethylene signaling
RT component EIN3 is important for the salt response in Arabidopsis.";
RL Plant Physiol. 157:854-865(2011).
RN [26]
RP INDUCTION BY LIGHT AND COLD.
RC STRAIN=cv. Wassilewskija-2;
RX PubMed=21471455; DOI=10.1073/pnas.1103741108;
RA Dong M.A., Farre E.M., Thomashow M.F.;
RT "Circadian clock-associated 1 and late elongated hypocotyl regulate
RT expression of the C-repeat binding factor (CBF) pathway in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:7241-7246(2011).
CC -!- FUNCTION: Exhibits cryoprotective activity toward stromal substrates
CC (e.g. LDH and rubisco) in chloroplasts and in protoplasts and confers
CC freezing tolerance to plants in a CBF-dependent manner (PubMed:1567390,
CC PubMed:11038526, PubMed:9826741, PubMed:17384167, PubMed:18540080,
CC PubMed:19563440). Protectant against various stresses (e.g. cold,
CC drought and heat stress) by preventing protein aggregation (e.g. LDH)
CC and attenuating enzyme inactivation (PubMed:18540080). Influences the
CC intrinsic curvature of the inner membrane of the chloroplast envelope,
CC and modulates the freeze-induced lamellar-to-hexagonal II phase
CC transitions that occur in regions where the plasma membrane is brought
CC into close apposition with the chloroplast envelope during freeze-
CC induced osmotic contraction (PubMed:9826741). Mediates a shift in the
CC melting curves of phospholipids-containing membranes to lower
CC temperatures (PubMed:20510170). Involved in the regulation of leaf
CC senescence by abscisic acid (ABA) in a VNI2-dependent manner
CC (PubMed:21673078). {ECO:0000269|PubMed:11038526,
CC ECO:0000269|PubMed:1567390, ECO:0000269|PubMed:17384167,
CC ECO:0000269|PubMed:18540080, ECO:0000269|PubMed:19563440,
CC ECO:0000269|PubMed:20510170, ECO:0000269|PubMed:21673078,
CC ECO:0000269|PubMed:9826741}.
CC -!- SUBUNIT: Forms homooligomers which interact with potential stromal
CC substrates in the stroma of chloroplasts (PubMed:17384167). Interacts
CC with the galactose headgroup of the chloroplast lipid
CC monogalactosyldiacylglycerol (MGDG) (PubMed:20510170).
CC {ECO:0000269|PubMed:17384167, ECO:0000269|PubMed:20510170}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC {ECO:0000269|PubMed:16668917, ECO:0000269|PubMed:17384167,
CC ECO:0000269|PubMed:8685269}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Comment=Additional isoforms seem to exist. {ECO:0000305};
CC Name=1;
CC IsoId=Q42512-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q42512-2; Sequence=VSP_057558;
CC -!- INDUCTION: Accumulates in leaves during cold acclimation (at protein
CC level) (PubMed:16668917, PubMed:17384167). Strongly induced by cold in
CC association with a gradual irreversible decrease of H3K27me3 in the
CC promoter region (PubMed:8193295, PubMed:9668134, PubMed:11706173,
CC PubMed:11779861, PubMed:12148528, PubMed:14745450, PubMed:15144380,
CC PubMed:16258011, PubMed:19470100, PubMed:19500304, PubMed:19563440).
CC Expressed transiently after moderate decrease in temperature (cooling)
CC through the CBF signaling cascade, thus leading to an enhanced
CC subsequent freezing resistance (PubMed:19563440). Accumulates in
CC response to high light, drought, high salt, polyethylene glycol (PEG)
CC and abscisic acid (ABA) (PubMed:8193295, PubMed:9668134,
CC PubMed:11779861, PubMed:12148528, PubMed:12785063, PubMed:21673078,
CC PubMed:21832142). Cold-mediated induction is light-dependent and light-
CC stimulated, and requires functional chloroplasts (PubMed:12148528,
CC PubMed:17384167, PubMed:21471455). Follow a circadian-regulated
CC expression with a progressive accumulation during the light phase and a
CC drop during the dark phase (PubMed:21471455).
CC {ECO:0000269|PubMed:11706173, ECO:0000269|PubMed:11779861,
CC ECO:0000269|PubMed:12148528, ECO:0000269|PubMed:12785063,
CC ECO:0000269|PubMed:14745450, ECO:0000269|PubMed:15144380,
CC ECO:0000269|PubMed:16258011, ECO:0000269|PubMed:16668917,
CC ECO:0000269|PubMed:17384167, ECO:0000269|PubMed:19470100,
CC ECO:0000269|PubMed:19500304, ECO:0000269|PubMed:19563440,
CC ECO:0000269|PubMed:21471455, ECO:0000269|PubMed:21673078,
CC ECO:0000269|PubMed:21832142, ECO:0000269|PubMed:8193295,
CC ECO:0000269|PubMed:9668134}.
CC -!- MISCELLANEOUS: Remaining soluble upon boiling in aqueous solution.
CC Oligomers can stay soluble with small structural change after boiling
CC and freeze-thaw treatments (PubMed:16668917, PubMed:17384167).
CC Predominantly unstructured in solution and mainly alpha-helical after
CC drying (PubMed:20510170). {ECO:0000269|PubMed:16668917,
CC ECO:0000269|PubMed:17384167, ECO:0000269|PubMed:20510170}.
CC -!- SIMILARITY: Belongs to the COR15 protein family. {ECO:0000305}.
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DR EMBL; X64138; CAA45499.1; -; mRNA.
DR EMBL; U01377; AAB87705.1; -; Unassigned_DNA.
DR EMBL; AC007087; AAD22999.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10135.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10136.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61537.1; -; Genomic_DNA.
DR EMBL; AY039853; AAK63957.1; -; mRNA.
DR EMBL; AY057640; AAL15271.1; -; mRNA.
DR EMBL; AY113048; AAM47356.1; -; mRNA.
DR PIR; S43769; S43769.
DR RefSeq; NP_001323750.1; NM_001336986.1. [Q42512-2]
DR RefSeq; NP_181782.1; NM_129815.5. [Q42512-1]
DR RefSeq; NP_850371.1; NM_180040.3. [Q42512-2]
DR AlphaFoldDB; Q42512; -.
DR SMR; Q42512; -.
DR STRING; 3702.AT2G42540.2; -.
DR iPTMnet; Q42512; -.
DR PaxDb; Q42512; -.
DR PRIDE; Q42512; -.
DR ProteomicsDB; 220551; -. [Q42512-1]
DR EnsemblPlants; AT2G42540.1; AT2G42540.1; AT2G42540. [Q42512-2]
DR EnsemblPlants; AT2G42540.2; AT2G42540.2; AT2G42540. [Q42512-1]
DR EnsemblPlants; AT2G42540.4; AT2G42540.4; AT2G42540. [Q42512-2]
DR GeneID; 818854; -.
DR Gramene; AT2G42540.1; AT2G42540.1; AT2G42540. [Q42512-2]
DR Gramene; AT2G42540.2; AT2G42540.2; AT2G42540. [Q42512-1]
DR Gramene; AT2G42540.4; AT2G42540.4; AT2G42540. [Q42512-2]
DR KEGG; ath:AT2G42540; -.
DR Araport; AT2G42540; -.
DR TAIR; locus:2041504; AT2G42540.
DR InParanoid; Q42512; -.
DR OMA; AVQNDDN; -.
DR OrthoDB; 1565886at2759; -.
DR PhylomeDB; Q42512; -.
DR PRO; PR:Q42512; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q42512; baseline and differential.
DR Genevisible; Q42512; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR GO; GO:0009570; C:chloroplast stroma; IDA:UniProtKB.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005534; F:galactose binding; IDA:UniProtKB.
DR GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR GO; GO:0007623; P:circadian rhythm; IGI:UniProtKB.
DR GO; GO:0009631; P:cold acclimation; IDA:UniProtKB.
DR GO; GO:0009819; P:drought recovery; IDA:UniProtKB.
DR GO; GO:0010286; P:heat acclimation; IDA:UniProtKB.
DR GO; GO:0010150; P:leaf senescence; IMP:TAIR.
DR GO; GO:0009667; P:plastid inner membrane organization; IDA:UniProtKB.
DR GO; GO:0051259; P:protein complex oligomerization; IDA:UniProtKB.
DR GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR GO; GO:0050821; P:protein stabilization; IDA:TAIR.
DR GO; GO:0010017; P:red or far-red light signaling pathway; IEP:TAIR.
DR GO; GO:0009737; P:response to abscisic acid; IEP:UniProtKB.
DR GO; GO:0009409; P:response to cold; IGI:UniProtKB.
DR GO; GO:0050826; P:response to freezing; IDA:TAIR.
DR GO; GO:0009644; P:response to high light intensity; IEP:UniProtKB.
DR GO; GO:0009416; P:response to light stimulus; IEP:UniProtKB.
DR GO; GO:0006970; P:response to osmotic stress; IGI:TAIR.
DR GO; GO:0009651; P:response to salt stress; IEP:UniProtKB.
DR GO; GO:0009414; P:response to water deprivation; IEP:UniProtKB.
DR DisProt; DP01057; -.
PE 1: Evidence at protein level;
KW Alternative splicing; Chloroplast; Lipid-binding; Plastid;
KW Reference proteome; Transit peptide.
FT TRANSIT 1..40
FT /note="Chloroplast"
FT /evidence="ECO:0000269|PubMed:16668917,
FT ECO:0000269|PubMed:8685269"
FT CHAIN 41..139
FT /note="Protein COLD-REGULATED 15A, chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_5001126580"
FT VAR_SEQ 1..12
FT /note="Missing (in isoform 2)"
FT /id="VSP_057558"
SQ SEQUENCE 139 AA; 14605 MW; 64EB38CACAD2990B CRC64;
MAMSFSGAVL TGMASSFHSG AKQSSFGAVR VGQKTQFVVV SQRKKSLIYA AKGDGNILDD
LNEATKKASD FVTDKTKEAL ADGEKAKDYV VEKNSETADT LGKEAEKAAA YVEEKGKEAA
NKAAEFAEGK AGEAKDATK
