CR19A_DANRE
ID CR19A_DANRE Reviewed; 242 AA.
AC Q1MTD4; A3KNQ7;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Uncharacterized protein C18orf19 homolog A;
GN ORFNames=si:ch211-105d11.2;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AL928820; CAK03686.1; -; Genomic_DNA.
DR EMBL; BC133959; AAI33960.1; -; mRNA.
DR RefSeq; NP_001038459.1; NM_001044994.2.
DR AlphaFoldDB; Q1MTD4; -.
DR SMR; Q1MTD4; -.
DR STRING; 7955.ENSDARP00000106065; -.
DR PaxDb; Q1MTD4; -.
DR Ensembl; ENSDART00000103692; ENSDARP00000094467; ENSDARG00000035985.
DR Ensembl; ENSDART00000151184; ENSDARP00000125742; ENSDARG00000035985.
DR GeneID; 562734; -.
DR KEGG; dre:562734; -.
DR CTD; 562734; -.
DR ZFIN; ZDB-GENE-030131-5627; fam210aa.
DR eggNOG; KOG4082; Eukaryota.
DR GeneTree; ENSGT00940000156554; -.
DR HOGENOM; CLU_085747_0_0_1; -.
DR InParanoid; Q1MTD4; -.
DR OMA; LAHGTCW; -.
DR OrthoDB; 1568689at2759; -.
DR PhylomeDB; Q1MTD4; -.
DR TreeFam; TF313283; -.
DR PRO; PR:Q1MTD4; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 19.
DR Bgee; ENSDARG00000035985; Expressed in muscle tissue and 28 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR InterPro; IPR045866; FAM210A/B-like.
DR InterPro; IPR009688; FAM210A/B-like_dom.
DR PANTHER; PTHR21377; PTHR21377; 1.
DR Pfam; PF06916; DUF1279; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..242
FT /note="Uncharacterized protein C18orf19 homolog A"
FT /id="PRO_0000274429"
FT TRANSMEM 92..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 76..188
FT /note="DUF1279"
FT REGION 57..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 188..237
FT /evidence="ECO:0000255"
SQ SEQUENCE 242 AA; 27852 MW; 5E8DDACD17F8698D CRC64;
MQRFVCSGVF RQTSVLLQIS PVSHCHTRRM QDSPSHRSLK QLISSQRWLN STTALCSPTS
QKTSASGQEE PDPLHDKSSG LIQRFKKTFK QYGKVMIPVH LLTSTMWFGT FYYAAMKGVN
LVPFLEYVGF PDKVVKLLEN SQSGYALTAY AMYKIATPAR YTVTLGGTSL SVKYLRKHGY
MSTPPPVKEY LQEKMEETKE RISGKMEETK DRFSERMEET KDKFNEKLQE TKDKVSFRKK
KE