CR1BA_BACTE
ID CR1BA_BACTE Reviewed; 1228 AA.
AC P0A374; P05517; Q45731;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Pesticidal crystal protein Cry1Ba;
DE AltName: Full=140 kDa crystal protein;
DE AltName: Full=Crystaline entomocidal protoxin;
DE AltName: Full=Insecticidal delta-endotoxin CryIB(a);
GN Name=cry1Ba; Synonyms=cryA4, cryIB(a);
OS Bacillus thuringiensis subsp. entomocidus.
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=1436;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=HD-110;
RA Soetaert P.;
RL Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Promotes colloidosmotic lysis by binding to the midgut
CC epithelial cells of insects. {ECO:0000250}.
CC -!- MISCELLANEOUS: Toxic segment of the protein is located in the N-
CC terminus. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the delta endotoxin family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X95704; CAA65003.1; -; Genomic_DNA.
DR AlphaFoldDB; P0A374; -.
DR SMR; P0A374; -.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0001897; P:cytolysis by symbiont of host cells; IEA:InterPro.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 1.20.190.10; -; 1.
DR Gene3D; 2.100.10.10; -; 1.
DR InterPro; IPR041587; Cry_V.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR038979; Pest_crys.
DR InterPro; IPR005638; Pest_crys_C.
DR InterPro; IPR005639; Pest_crys_N.
DR InterPro; IPR036716; Pest_crys_N_sf.
DR InterPro; IPR001178; Pest_cryst_cen_dom.
DR InterPro; IPR036399; Pest_cryst_cen_dom_sf.
DR PANTHER; PTHR37003; PTHR37003; 1.
DR Pfam; PF17997; Cry1Ac_D5; 1.
DR Pfam; PF03944; Endotoxin_C; 1.
DR Pfam; PF00555; Endotoxin_M; 1.
DR Pfam; PF03945; Endotoxin_N; 1.
DR SUPFAM; SSF49785; SSF49785; 1.
DR SUPFAM; SSF51096; SSF51096; 1.
DR SUPFAM; SSF56849; SSF56849; 1.
PE 3: Inferred from homology;
KW Sporulation; Toxin; Virulence.
FT CHAIN 1..1228
FT /note="Pesticidal crystal protein Cry1Ba"
FT /id="PRO_0000174029"
FT REGION 423..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1228 AA; 139622 MW; 3DA2A4DBF59C95C3 CRC64;
MTSNRKNENE IINAVSNHSA QMDLLPDARI EDSLCIAEGN NIDPFVSAST VQTGINIAGR
ILGVLGVPFA GQLASFYSFL VGELWPRGRD QWEIFLEHVE QLINQQITEN ARNTALARLQ
GLGDSFRAYQ QSLEDWLENR DDARTRSVLH TQYIALELDF LNAMPLFAIR NQEVPLLMVY
AQAANLHLLL LRDASLFGSE FGLTSQEIQR YYERQVERTR DYSDYCVEWY NTGLNSLRGT
NAASWVRYNQ FRRDLTLGVL DLVALFPSYD TRTYPINTSA QLTREVYTDA IGATGVNMAS
MNWYNNNAPS FSAIEAAAIR SPHLLDFLEQ LTIFSASSRW SNTRHMTYWR GHTIQSRPIG
GGLNTSTHGA TNTSINPVTL RFASRDVYRT ESYAGVLLWG IYLEPIHGVP TVRFNFTNPQ
NISDRGTANY SQPYESPGLQ LKDSETELPP ETTERPNYES YSHRLSHIGI ILQSRVNVPV
YSWTHRSADR TNTIGPNRIT QIPMVKASEL PQGTTVVRGP GFTGGDILRR TNTGGFGPIR
VTVNGPLTQR YRIGFRYAST VDFDFFVSRG GTTVNNFRFL RTMNSGDELK YGNFVRRAFT
TPFTFTQIQD IIRTSIQGLS GNGEVYIDKI EIIPVTATFE AEYDLERAQE AVNALFTNTN
PRRLKTDVTD YHIDQVSNLV ACLSDEFCLD EKRELLEKVK YAKRLSDERN LLQDPNFTSI
NKQPDFISTN EQSNFTSIHE QSEHGWWGSE NITIQEGNDV FKENYVTLPG TFNECYPTYL
YQKIGESELK AYTRYQLRGY IEDSQDLEIY LIRYNAKHET LDVPGTESLW PLSVESPIGR
CGEPNRCAPH FEWNPDLDCS CRDGEKCAHH SHHFSLDIDV GCTDLHENLG VWVVFKIKTQ
EGHARLGNLE FIEEKPLLGE ALSRVKRAEK KWRDKREKLQ LETKRVYTEA KEAVDALFVD
SQYDRLQADT NIGMIHAADK LVHRIREAYL SELPVIPGVN AEIFEELEGH IITAISLYDA
RNVVKNGDFN NGLTCWNVKG HVDVQQSHHR SDLVIPEWEA EVSQAVRVCP GCGYILRVTA
YKEGYGEGCV TIHEIENNTD ELKFKNREEE EVYPTDTGTC NDYTAHQGTA GCADACNSRN
AGYEDAYEVD TTASVNYKPT YEEETYTDVR RDNHCEYDRG YVNYPPVPAG YVTKELEYFP
ETDTVWIEIG ETEGKFIVDS VELLLMEE