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CR1BA_BACTE
ID   CR1BA_BACTE             Reviewed;        1228 AA.
AC   P0A374; P05517; Q45731;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Pesticidal crystal protein Cry1Ba;
DE   AltName: Full=140 kDa crystal protein;
DE   AltName: Full=Crystaline entomocidal protoxin;
DE   AltName: Full=Insecticidal delta-endotoxin CryIB(a);
GN   Name=cry1Ba; Synonyms=cryA4, cryIB(a);
OS   Bacillus thuringiensis subsp. entomocidus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1436;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HD-110;
RA   Soetaert P.;
RL   Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Promotes colloidosmotic lysis by binding to the midgut
CC       epithelial cells of insects. {ECO:0000250}.
CC   -!- MISCELLANEOUS: Toxic segment of the protein is located in the N-
CC       terminus. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the delta endotoxin family. {ECO:0000305}.
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DR   EMBL; X95704; CAA65003.1; -; Genomic_DNA.
DR   AlphaFoldDB; P0A374; -.
DR   SMR; P0A374; -.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0001897; P:cytolysis by symbiont of host cells; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.190.10; -; 1.
DR   Gene3D; 2.100.10.10; -; 1.
DR   InterPro; IPR041587; Cry_V.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR038979; Pest_crys.
DR   InterPro; IPR005638; Pest_crys_C.
DR   InterPro; IPR005639; Pest_crys_N.
DR   InterPro; IPR036716; Pest_crys_N_sf.
DR   InterPro; IPR001178; Pest_cryst_cen_dom.
DR   InterPro; IPR036399; Pest_cryst_cen_dom_sf.
DR   PANTHER; PTHR37003; PTHR37003; 1.
DR   Pfam; PF17997; Cry1Ac_D5; 1.
DR   Pfam; PF03944; Endotoxin_C; 1.
DR   Pfam; PF00555; Endotoxin_M; 1.
DR   Pfam; PF03945; Endotoxin_N; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF51096; SSF51096; 1.
DR   SUPFAM; SSF56849; SSF56849; 1.
PE   3: Inferred from homology;
KW   Sporulation; Toxin; Virulence.
FT   CHAIN           1..1228
FT                   /note="Pesticidal crystal protein Cry1Ba"
FT                   /id="PRO_0000174029"
FT   REGION          423..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        423..439
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1228 AA;  139622 MW;  3DA2A4DBF59C95C3 CRC64;
     MTSNRKNENE IINAVSNHSA QMDLLPDARI EDSLCIAEGN NIDPFVSAST VQTGINIAGR
     ILGVLGVPFA GQLASFYSFL VGELWPRGRD QWEIFLEHVE QLINQQITEN ARNTALARLQ
     GLGDSFRAYQ QSLEDWLENR DDARTRSVLH TQYIALELDF LNAMPLFAIR NQEVPLLMVY
     AQAANLHLLL LRDASLFGSE FGLTSQEIQR YYERQVERTR DYSDYCVEWY NTGLNSLRGT
     NAASWVRYNQ FRRDLTLGVL DLVALFPSYD TRTYPINTSA QLTREVYTDA IGATGVNMAS
     MNWYNNNAPS FSAIEAAAIR SPHLLDFLEQ LTIFSASSRW SNTRHMTYWR GHTIQSRPIG
     GGLNTSTHGA TNTSINPVTL RFASRDVYRT ESYAGVLLWG IYLEPIHGVP TVRFNFTNPQ
     NISDRGTANY SQPYESPGLQ LKDSETELPP ETTERPNYES YSHRLSHIGI ILQSRVNVPV
     YSWTHRSADR TNTIGPNRIT QIPMVKASEL PQGTTVVRGP GFTGGDILRR TNTGGFGPIR
     VTVNGPLTQR YRIGFRYAST VDFDFFVSRG GTTVNNFRFL RTMNSGDELK YGNFVRRAFT
     TPFTFTQIQD IIRTSIQGLS GNGEVYIDKI EIIPVTATFE AEYDLERAQE AVNALFTNTN
     PRRLKTDVTD YHIDQVSNLV ACLSDEFCLD EKRELLEKVK YAKRLSDERN LLQDPNFTSI
     NKQPDFISTN EQSNFTSIHE QSEHGWWGSE NITIQEGNDV FKENYVTLPG TFNECYPTYL
     YQKIGESELK AYTRYQLRGY IEDSQDLEIY LIRYNAKHET LDVPGTESLW PLSVESPIGR
     CGEPNRCAPH FEWNPDLDCS CRDGEKCAHH SHHFSLDIDV GCTDLHENLG VWVVFKIKTQ
     EGHARLGNLE FIEEKPLLGE ALSRVKRAEK KWRDKREKLQ LETKRVYTEA KEAVDALFVD
     SQYDRLQADT NIGMIHAADK LVHRIREAYL SELPVIPGVN AEIFEELEGH IITAISLYDA
     RNVVKNGDFN NGLTCWNVKG HVDVQQSHHR SDLVIPEWEA EVSQAVRVCP GCGYILRVTA
     YKEGYGEGCV TIHEIENNTD ELKFKNREEE EVYPTDTGTC NDYTAHQGTA GCADACNSRN
     AGYEDAYEVD TTASVNYKPT YEEETYTDVR RDNHCEYDRG YVNYPPVPAG YVTKELEYFP
     ETDTVWIEIG ETEGKFIVDS VELLLMEE
 
 
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