ID   CR1IB_BACTE             Reviewed;         719 AA.
AC   Q45709;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Pesticidal crystal protein Cry1Ib;
DE   AltName: Full=81 kDa crystal protein;
DE   AltName: Full=Crystaline entomocidal protoxin;
DE   AltName: Full=Insecticidal delta-endotoxin CryII(b);
GN   Name=cry1Ib; Synonyms=cryII(b), cryV, cryV465;
OS   Bacillus thuringiensis subsp. entomocidus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1436;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BP465;
RX   PubMed=7793960; DOI=10.1128/aem.61.6.2402-2407.1995;
RA   Shin B.-S., Park S.-H., Choi S.-K., Koo B.T., Lee S.T., Kim J.I.;
RT   "Distribution of cryV-type insecticidal protein genes in Bacillus
RT   thuringiensis and cloning of cryV-type genes from Bacillus thuringiensis
RT   subsp. kurstaki and Bacillus thuringiensis subsp. entomocidus.";
RL   Appl. Environ. Microbiol. 61:2402-2407(1995).
CC   -!- FUNCTION: Promotes colloidosmotic lysis by binding to the midgut
CC       epithelial cells of certain coleopteran and lepidopteran species.
CC       Active on Plutella xylostella but not on Bombyx mori.
CC   -!- DEVELOPMENTAL STAGE: The crystal protein is produced during sporulation
CC       and is accumulated both as an inclusion and as part of the spore coat.
CC   -!- MISCELLANEOUS: Toxic segment of the protein is located in the N-
CC       terminus.
CC   -!- SIMILARITY: Belongs to the delta endotoxin family. {ECO:0000305}.
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DR   EMBL; U07642; AAA82114.1; -; Genomic_DNA.
DR   PIR; I40590; I40590.
DR   AlphaFoldDB; Q45709; -.
DR   SMR; Q45709; -.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0001897; P:cytolysis by symbiont of host cells; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.190.10; -; 1.
DR   Gene3D; 2.100.10.10; -; 1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR038979; Pest_crys.
DR   InterPro; IPR005638; Pest_crys_C.
DR   InterPro; IPR005639; Pest_crys_N.
DR   InterPro; IPR036716; Pest_crys_N_sf.
DR   InterPro; IPR001178; Pest_cryst_cen_dom.
DR   InterPro; IPR036399; Pest_cryst_cen_dom_sf.
DR   PANTHER; PTHR37003; PTHR37003; 1.
DR   Pfam; PF03944; Endotoxin_C; 1.
DR   Pfam; PF00555; Endotoxin_M; 1.
DR   Pfam; PF03945; Endotoxin_N; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF51096; SSF51096; 1.
DR   SUPFAM; SSF56849; SSF56849; 1.
PE   2: Evidence at transcript level;
KW   Sporulation; Toxin; Virulence.
FT   CHAIN           1..719
FT                   /note="Pesticidal crystal protein Cry1Ib"
FT                   /id="PRO_0000174049"
SQ   SEQUENCE   719 AA;  81295 MW;  E8210ABEAE97688E CRC64;
     MKLKNPDKHQ SLSSNAKVDK IATDSLKNET DIELKNMNNE DYLRMSEHES IDPFVSASTI
     QTGIGIAGKI LGTLGVPFAG QIASLYSFIL GELWPKGKSQ WEIFMEHVEE IINQKILTYA
     RNKALSDLRG LGDALAVYHE SLESWVENRN NTRARSVVKN QYIALELMFV QKLPSFAVSG
     EEVPLLPIYA QAANLHLLLL RDASIFGKEW GLSASEISTF YNRQVERTRD YSDHCIKWYN
     TGLNNLRGTN AKSWVRYNQF RKDMTLMVLD LVALFPSYDT LVYPIKTTSQ LTREVYTDAI
     GTVHPNQAFA STTWYNNNAP SFSAIEAAVI RSPHLLDFLE KVTIYSLLSR WSNTQYMNMW
     GGHRLESRPI GGALNTSTQG STNTSINPVT LQFTSRDVYR TESLAGLNLF LTQPVNGVPR
     VDFHWKFPTL PIASDNFYYL GYAGVGTQLQ DSENELPPET TGQPNYESYS HRLSHIGLIS
     ASHVKALVYS WTHRSADRTN TIEPNSITQI PLVKAFNLSS GAAVVRGPGF TGGDILRRTN
     TGTFGDIRVN INPPFAQRYR VRIRYASTTD LQFHTSINGK AINQGNFSAT MNRGEDLDYK
     TFRTIGFTTP FSFSDVQSTF TIGAWNFSSG NEVYIDRIEF VPVEVTYEAE YDFEKAQEKV
     TALFTSTNPR GLKTDVKDYH IDQVSNLVES LSDEFYLDEK RELFEIVKYA KQIHIERNM