ID   CR1JB_BACTU             Reviewed;        1170 AA.
AC   Q45716;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Pesticidal crystal protein Cry1Jb;
DE   AltName: Full=134 kDa crystal protein;
DE   AltName: Full=Crystaline entomocidal protoxin;
DE   AltName: Full=Insecticidal delta-endotoxin CryIJ(b);
GN   Name=cry1Jb; Synonyms=cryET1, cryIJ(b);
OS   Bacillus thuringiensis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1428;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NRRL B-18973 / EG5092;
RA   von Tersch M.A., Gonzalez J.M. Jr.;
RT   "Bacillus thuringiensis cryET1 toxin gene and protein toxic to lepidopteran
RT   insects.";
RL   Patent number US5356623, 18-OCT-1994.
CC   -!- FUNCTION: Promotes colloidosmotic lysis by binding to the midgut
CC       epithelial cells of many lepidopteran larvae. Toxic to Plutella
CC       xylostella.
CC   -!- DEVELOPMENTAL STAGE: The crystal protein is produced during sporulation
CC       and is accumulated both as an inclusion and as part of the spore coat.
CC   -!- MISCELLANEOUS: Toxic segment of the protein is located in the N-
CC       terminus.
CC   -!- SIMILARITY: Belongs to the delta endotoxin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U31527; AAA98959.1; -; Unassigned_DNA.
DR   AlphaFoldDB; Q45716; -.
DR   SMR; Q45716; -.
DR   PRIDE; Q45716; -.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0001897; P:cytolysis by symbiont of host cells; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.190.10; -; 1.
DR   Gene3D; 2.100.10.10; -; 1.
DR   InterPro; IPR041587; Cry_V.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR038979; Pest_crys.
DR   InterPro; IPR005638; Pest_crys_C.
DR   InterPro; IPR005639; Pest_crys_N.
DR   InterPro; IPR036716; Pest_crys_N_sf.
DR   InterPro; IPR001178; Pest_cryst_cen_dom.
DR   InterPro; IPR036399; Pest_cryst_cen_dom_sf.
DR   PANTHER; PTHR37003; PTHR37003; 1.
DR   Pfam; PF17997; Cry1Ac_D5; 1.
DR   Pfam; PF03944; Endotoxin_C; 1.
DR   Pfam; PF00555; Endotoxin_M; 1.
DR   Pfam; PF03945; Endotoxin_N; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF51096; SSF51096; 1.
DR   SUPFAM; SSF56849; SSF56849; 1.
PE   2: Evidence at transcript level;
KW   Sporulation; Toxin; Virulence.
FT   CHAIN           1..1170
FT                   /note="Pesticidal crystal protein Cry1Jb"
FT                   /id="PRO_0000174053"
SQ   SEQUENCE   1170 AA;  133554 MW;  B053B9619B78DC19 CRC64;
     MEINNQNQCI PYNCLSNPEE VLLDGERILP DIDPLEVSMS LLQFLLNNFV PGGGFISGLF
     DKIWGALRPS DWELFLAQIE QLIDQRIEAT VRAKAIAELE GLGRSFQLYV EAFKEWEETP
     DNTAARSRVT ERFRIIDAQI EANIPSFRIP GFEVPLLSVY AQAANLHLAL LRDSVIFGER
     WGLTTTNVND IYNRQVKRIH EYSDHCVDTY KTELERLGFT SRAQWKIYNQ FRRELTLTVL
     DIVAVFPNYD GKLYPIQTKS ELTREIYTSP VSEYYYGAIN NYNQNGIQTE RQIRQPHLMD
     FFNTMTMYTS YNRREYYWSG LEMTAYFTGF AGPQVSFPLA GTRGDAAPPF NVRSVNDGIY
     RILSAPFYSA PFLGTSVLGS RGEEFMFALN NISPPPSARY RNPGTVDSLV SIPPQDNSVP
     PHRGSSHRLS HVTMRNSSPI FHWTHRSATT TNRINSDVIT QIPMVKAYNL HAGATVVRGP
     GFTGGDILRR TSNGMVVTLR VDASAVRNQR YRIRFRYAAT SNFYFVVRRG NLGVNGREIM
     KTMSTGEELK SASFVLGEFI TPFNFFENQV PLQIEIQSLS PGGEVYLDKI EFIPADTTFE
     AEYDLERAQK AVNALFTSTN QRGLKTDVTD YHIDQVSNLV ECLSDEFCLD EKRELSEKVK
     HAKRLSDERN LLQDPNFTSI NGQLDRGWRG STDITIQGGN DVFKENYVTL PGTFDECYPT
     YLYQKIDESK LKAYTRYELR GYIEDSQDLE VYLIRYNAKH ETLNVPGTDS LRTLSVESQN
     GRCGELNRCM PHIKWNPDVD CSCRDGEKCA HHSHHFSLDI DVGCTDLQED LGVWVVFKIK
     TQEGYARLGN LEFIEEKPLV GEALSRVKRA EKKWRDKREK LELETKRVYT EAKEAVDALF
     VDSQYDRLQA DTNIGMIHAA DKLVHRICET YLPELPFIPG INAIIFEELE NRISTAFFLY
     EARNVINNGD FNNGLTCWNV KGHVDVQQSH HRSVLVIPEW EAEVSQKVRV CPGRGYILRV
     TAYKEGYGEG CVTIHEIEDN TDELKFRNCE EEGDYSNDTG TCNDYPASQG AAGCADVCNS
     RNVGYKDAYE TNTSASVNYK PTYEEETYTD VREDNHCEYD RGYVNYPPLP AGYVTKELEY
     FPETDTVWIE IGETEGKFIV DSVELLLMEE