位置:首页 > 蛋白库 > CR7AB_BACUK
CR7AB_BACUK
ID   CR7AB_BACUK             Reviewed;        1138 AA.
AC   Q45708;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Pesticidal crystal protein Cry7Ab;
DE   AltName: Full=130 kDa crystal protein;
DE   AltName: Full=Crystaline entomocidal protoxin;
DE   AltName: Full=Insecticidal delta-endotoxin CryVIIA(b);
GN   Name=cry7Ab; Synonyms=cryVIIA(b);
OS   Bacillus thuringiensis serovar kumamotoensis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=132267;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HD867;
RA   Payne J.M., Fu J.M.;
RT   "Coleopteran-active Bacillus thuringiensis isolates and genes encoding
RT   coleopteran-active toxins.";
RL   Patent number US5286486, 15-FEB-1994.
CC   -!- FUNCTION: Promotes colloidosmotic lysis by binding to the midgut
CC       epithelial cells of Coleoptera.
CC   -!- DEVELOPMENTAL STAGE: The crystal protein is produced during sporulation
CC       and is accumulated both as an inclusion and as part of the spore coat.
CC   -!- MISCELLANEOUS: Toxic segment of the protein is located in the N-
CC       terminus.
CC   -!- SIMILARITY: Belongs to the delta endotoxin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U04368; AAA21121.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q45708; -.
DR   SMR; Q45708; -.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0001897; P:cytolysis by symbiont of host cells; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.190.10; -; 1.
DR   Gene3D; 2.100.10.10; -; 1.
DR   InterPro; IPR041587; Cry_V.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR038979; Pest_crys.
DR   InterPro; IPR005638; Pest_crys_C.
DR   InterPro; IPR005639; Pest_crys_N.
DR   InterPro; IPR036716; Pest_crys_N_sf.
DR   InterPro; IPR001178; Pest_cryst_cen_dom.
DR   InterPro; IPR036399; Pest_cryst_cen_dom_sf.
DR   PANTHER; PTHR37003; PTHR37003; 1.
DR   Pfam; PF17997; Cry1Ac_D5; 1.
DR   Pfam; PF03944; Endotoxin_C; 1.
DR   Pfam; PF00555; Endotoxin_M; 1.
DR   Pfam; PF03945; Endotoxin_N; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   SUPFAM; SSF51096; SSF51096; 1.
DR   SUPFAM; SSF56849; SSF56849; 1.
PE   2: Evidence at transcript level;
KW   Sporulation; Toxin; Virulence.
FT   CHAIN           1..1138
FT                   /note="Pesticidal crystal protein Cry7Ab"
FT                   /id="PRO_0000174074"
SQ   SEQUENCE   1138 AA;  129659 MW;  E12DC80C0A56D1DA CRC64;
     MNLNNLGGYE DSNRTLNNSL NYPTQKALSP SLKNMNYQDF LSITEREQPE ALASGNTAIN
     TVVSVTGATL SALGVPGASF ITNFYLKITG LLWPHDKNIW DEFMTEVETL IEQKIEQYAR
     NKALAELEGL GNNLTIYQQA LEDWLNNPDD PATITRVIDR FRILDALFES YMPSFRVAGY
     EIPLLTVYAQ AANLHLALLR DSTLYGDKWE FTQNNIEENY NRQKKHISEY SNHCVKWYNS
     GLSRLNGSTY EQWINYNRFR REMILMVLDI AAVFPIYDPR MYSMETSTQL TREVYTDPIS
     LSISNPGIGP SFSQMENTAI RTPHLVDYLD ELYIYTSKYK AFSHEIQPDL FYWSAHKVSF
     KQSEQSNLYT TGIYGKTSGY ISSGAYSFRG NDIYRTLAAP SVVVYPYTQN YGVEQVEFYG
     VKGHVHYRGD NKYDLTYDSI DQLPPDGEPI HEKYTHRLCH ATAISKSTPD YDNATIPIFS
     WTHRSAEYYN RIYPNKITKI PAVKMYKLGD TSTVVKGPGF TGGDLVKRGS NGYIGDIKAT
     VNSPLSQNYR VRVRYATNVS GQFNVYINDK ITLQRKFQNT VETIGEGKDL TYGSFGYIEY
     STTIQFPDKH PKITLHLSDL SNNSSFYVDS IEFIPVDVNY DEKEKLEKAQ KAVNTLFTEG
     RNALQKDVTD YKVDQVSILV DCISGDLYPN EKRELQNLVK YAKRLSYSRN LLLDPTFDSI
     NSSEENGWYG SNGIVIGNGD FVFKGNYLIF SGTNDTQYPT YLYQKIDESK LKEYTRYKLK
     GFIESSQDLE AYVIRYDAKH RTLDVSDNLL PDILPENTCG EPNRCAAQQY LDENPSSECS
     SMQDGILSDS HSFSLNIDIG SINHNENLGI WVLFKISTLE GYAKFGNLEV IEDGPVIGEA
     LARVKRQETK WRNKLAQLTT ETQAIYTRAK QALDNLFANA QDSHLKIDVT FAEIAAARKI
     VQSIREAYMS WLSVVPGVNH PIFTELSERV QRAFQLYDVR NVVRNGRFLN GLSDWIVTSD
     VKVQEENGNN VLVLNNWDAQ VLQNVKLYQD RGYILRVTAR KIGIGEGYIT ITDEEGHTVQ
     LRFTACEVID ASNAFISGYI TKELEFFPDT EKVHIEIGET EGIFLVESIE LFLMEELC
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024