ID   CRBLF_VESMG             Reviewed;          13 AA.
AC   P0C1M2;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 22.
DE   RecName: Full=Vespid chemotactic peptide 5f;
DE            Short=VCP 5f;
OS   Vespa magnifica (Hornet).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Vespoidea;
OC   Vespidae; Vespinae; Vespa.
OX   NCBI_TaxID=202807;
RN   [1]
RP   PROTEIN SEQUENCE, AND MINIMAL INHIBITORY CONCENTRATION.
RC   TISSUE=Venom;
RX   PubMed=16330062; DOI=10.1016/j.toxicon.2005.10.015;
RA   Xu X., Li J., Lu Q., Yang H., Zhang Y., Lai R.;
RT   "Two families of antimicrobial peptides from wasp (Vespa magnifica)
RT   venom.";
RL   Toxicon 47:249-253(2006).
CC   -!- FUNCTION: Mast cell degranulating peptide (By similarity). Has little
CC       hemolytic activity. Shows antimicrobial activity against the Gram-
CC       negative bacteria E.coli ATCC 25922 (MIC=30 ug/ml), the Gram-positive
CC       bacteria S.aureus ATCC 2592 (MIC=10 ug/ml) and the fungus C.albicans
CC       ATCC 2002 (MIC=25 ug/ml). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- SIMILARITY: Belongs to the MCD family. Crabrolin subfamily.
CC       {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0044179; P:hemolysis in another organism; IEA:UniProtKB-KW.
DR   GO; GO:0043303; P:mast cell degranulation; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Antibiotic; Antimicrobial; Cytolysis; Direct protein sequencing;
KW   Fungicide; Hemolysis; Mast cell degranulation; Secreted.
FT   PEPTIDE         1..13
FT                   /note="Vespid chemotactic peptide 5f"
FT                   /id="PRO_0000246008"
FT   MOD_RES         13
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   13 AA;  1462 MW;  786D40390DFE4774 CRC64;
     FLPIPRPILL GLL