ID   CRCB1_CORJK             Reviewed;         140 AA.
AC   Q4JSG7;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Putative fluoride ion transporter CrcB 1;
GN   Name=crcB1; OrderedLocusNames=jk2058;
OS   Corynebacterium jeikeium (strain K411).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=306537;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K411;
RX   PubMed=15968079; DOI=10.1128/jb.187.13.4671-4682.2005;
RA   Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A.,
RA   Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F.,
RA   Rupp O., Schneiker S., Viehoever P., Puehler A.;
RT   "Complete genome sequence and analysis of the multiresistant nosocomial
RT   pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the
RT   human skin flora.";
RL   J. Bacteriol. 187:4671-4682(2005).
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR931997; CAI38240.1; -; Genomic_DNA.
DR   RefSeq; WP_005292462.1; NC_007164.1.
DR   AlphaFoldDB; Q4JSG7; -.
DR   SMR; Q4JSG7; -.
DR   STRING; 306537.jk2058; -.
DR   EnsemblBacteria; CAI38240; CAI38240; jk2058.
DR   KEGG; cjk:jk2058; -.
DR   eggNOG; ENOG5032DWT; Bacteria.
DR   HOGENOM; CLU_114342_2_0_11; -.
DR   OMA; AVVCRYA; -.
DR   OrthoDB; 98047at85007; -.
DR   Proteomes; UP000000545; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..140
FT                   /note="Putative fluoride ion transporter CrcB 1"
FT                   /id="PRO_0000252870"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   140 AA;  14209 MW;  73B5A200A9E35AD2 CRC64;
     MNTGATLIEL LAVALGGGTG AAARYVLDTH LKSKHGWAPL WSLAVVNLLG TVVLGLVLGY
     TSQHLDGAAG STSAGETQDI LYPLLGIGLA GGFTTFSTVM VEVFTRPQPA RRIAGVVGMA
     VVCCAVFLPA LWCGALLAGA