CRCB1_DEIGD
ID CRCB1_DEIGD Reviewed; 126 AA.
AC Q1J232;
DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Putative fluoride ion transporter CrcB 1 {ECO:0000255|HAMAP-Rule:MF_00454};
GN Name=crcB1 {ECO:0000255|HAMAP-Rule:MF_00454}; OrderedLocusNames=Dgeo_0149;
OS Deinococcus geothermalis (strain DSM 11300 / AG-3a).
OC Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=319795;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11300 / AG-3a;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Daly M.J.,
RA Fredrickson J.K., Makarova K.S., Gaidamakova E.K., Zhai M., Richardson P.;
RT "Complete sequence of chromosome 1 of Deinococcus geothermalis DSM 11300.";
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC thus reducing its toxicity. {ECO:0000255|HAMAP-Rule:MF_00454}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00454};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00454}.
CC -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000255|HAMAP-
CC Rule:MF_00454}.
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DR EMBL; CP000359; ABF44452.1; -; Genomic_DNA.
DR RefSeq; WP_011529299.1; NC_008025.1.
DR AlphaFoldDB; Q1J232; -.
DR SMR; Q1J232; -.
DR STRING; 319795.Dgeo_0149; -.
DR EnsemblBacteria; ABF44452; ABF44452; Dgeo_0149.
DR KEGG; dge:Dgeo_0149; -.
DR eggNOG; COG0239; Bacteria.
DR HOGENOM; CLU_114342_2_3_0; -.
DR OMA; TWMLETH; -.
DR OrthoDB; 1942863at2; -.
DR Proteomes; UP000002431; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR HAMAP; MF_00454; CrcB; 1.
DR InterPro; IPR003691; CrcB.
DR PANTHER; PTHR28259; PTHR28259; 1.
DR Pfam; PF02537; CRCB; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..126
FT /note="Putative fluoride ion transporter CrcB 1"
FT /id="PRO_0000252875"
FT TRANSMEM 5..25
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
SQ SEQUENCE 126 AA; 12702 MW; D660B14DC4BB75C4 CRC64;
MKAGLWLWLM LGGAVGAVCR QGVVLALAPL VARLGFPVAV LGINVLGSFL LGLTLALAGR
GVWPPEVRVA FGTGVLGAFT TFSTFSTELD ELLGRGAVGL AALYAGLSVG LGLLAAVAGR
LLGTRL