ID   CRCB1_PROMA             Reviewed;         124 AA.
AC   Q7V9N6;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Putative fluoride ion transporter CrcB 1 {ECO:0000255|HAMAP-Rule:MF_00454};
GN   Name=crcB1 {ECO:0000255|HAMAP-Rule:MF_00454}; OrderedLocusNames=Pro_1793;
OS   Prochlorococcus marinus (strain SARG / CCMP1375 / SS120).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=167539;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SARG / CCMP1375 / SS120;
RX   PubMed=12917486; DOI=10.1073/pnas.1733211100;
RA   Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M.,
RA   Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S.,
RA   Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J.,
RA   Tandeau de Marsac N., Weissenbach J., Wincker P., Wolf Y.I., Hess W.R.;
RT   "Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a
RT   nearly minimal oxyphototrophic genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003).
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000255|HAMAP-Rule:MF_00454}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00454}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
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DR   EMBL; AE017126; AAQ00837.1; -; Genomic_DNA.
DR   RefSeq; NP_876184.1; NC_005042.1.
DR   RefSeq; WP_011125942.1; NC_005042.1.
DR   AlphaFoldDB; Q7V9N6; -.
DR   SMR; Q7V9N6; -.
DR   STRING; 167539.Pro_1793; -.
DR   EnsemblBacteria; AAQ00837; AAQ00837; Pro_1793.
DR   GeneID; 54201122; -.
DR   KEGG; pma:Pro_1793; -.
DR   PATRIC; fig|167539.5.peg.1894; -.
DR   eggNOG; COG0239; Bacteria.
DR   HOGENOM; CLU_114342_2_1_3; -.
DR   OrthoDB; 1942863at2; -.
DR   Proteomes; UP000001420; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR   HAMAP; MF_00454; CrcB; 1.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..124
FT                   /note="Putative fluoride ion transporter CrcB 1"
FT                   /id="PRO_0000110151"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
SQ   SEQUENCE   124 AA;  13979 MW;  6B85BEB02CAF8F51 CRC64;
     MHSKLNIQSK QLYKIFLLIV GSILGAILRW KLNNYFWVNI SGAALLGLIV GLRAGSRIQF
     FLVIGFCGSF TTFSGWILDV FDLFRTGFFW KAAGLICSNL LGGFTALSVT FWIGRKIRHL
     FIPQ