ID   CRCB1_PROMP             Reviewed;         109 AA.
AC   Q7UZM7;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Putative fluoride ion transporter CrcB 1;
GN   Name=crcB1; OrderedLocusNames=PMM1631;
OS   Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 /
OS   MED4).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=59919;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1986 / NIES-2087 / MED4;
RX   PubMed=12917642; DOI=10.1038/nature01947;
RA   Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A.,
RA   Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L.,
RA   Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C.,
RA   Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R.,
RA   Chisholm S.W.;
RT   "Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche
RT   differentiation.";
RL   Nature 424:1042-1047(2003).
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000305}.
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DR   EMBL; BX548174; CAE20090.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q7UZM7; -.
DR   SMR; Q7UZM7; -.
DR   STRING; 59919.PMM1631; -.
DR   EnsemblBacteria; CAE20090; CAE20090; PMM1631.
DR   KEGG; pmm:PMM1631; -.
DR   HOGENOM; CLU_2181556_0_0_3; -.
DR   OMA; WISRKIT; -.
DR   Proteomes; UP000001026; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR003691; CrcB.
DR   Pfam; PF02537; CRCB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..109
FT                   /note="Putative fluoride ion transporter CrcB 1"
FT                   /id="PRO_0000110155"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   109 AA;  12971 MW;  B63EC34ABF98C46A CRC64;
     MNKKYLLTFL LTAYCATFLR FYFKNNFVIS IIGSFLYGFF ISRKISKSKK EILFSGFFAC
     FTSFSGFVHF LYQFIIQGYY LKLFIYLNVI VILNLIIMYI GFQLSRKIT