ID   CRCB1_SYNS9             Reviewed;         126 AA.
AC   Q3B0L8;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Putative fluoride ion transporter CrcB 1 {ECO:0000255|HAMAP-Rule:MF_00454};
GN   Name=crcB1 {ECO:0000255|HAMAP-Rule:MF_00454};
GN   OrderedLocusNames=Syncc9902_0135;
OS   Synechococcus sp. (strain CC9902).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=316279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC9902;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Synechococcus sp. CC9902.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000255|HAMAP-Rule:MF_00454}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00454}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
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DR   EMBL; CP000097; ABB25110.1; -; Genomic_DNA.
DR   RefSeq; WP_011358977.1; NC_007513.1.
DR   AlphaFoldDB; Q3B0L8; -.
DR   SMR; Q3B0L8; -.
DR   STRING; 316279.Syncc9902_0135; -.
DR   EnsemblBacteria; ABB25110; ABB25110; Syncc9902_0135.
DR   KEGG; sye:Syncc9902_0135; -.
DR   eggNOG; COG0239; Bacteria.
DR   HOGENOM; CLU_114342_2_3_3; -.
DR   OMA; HFEPMVP; -.
DR   OrthoDB; 1942863at2; -.
DR   Proteomes; UP000002712; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR   HAMAP; MF_00454; CrcB; 1.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..126
FT                   /note="Putative fluoride ion transporter CrcB 1"
FT                   /id="PRO_0000252952"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
SQ   SEQUENCE   126 AA;  12842 MW;  274AE174FD5BE2EA CRC64;
     MAGSALEALL VGIGAIPGAW LRLKAVNHFE PMVPKKHWGT FAVNVIACFG LGLVLALYQS
     CSAKTGLALL IGVGFFGSLS TFSTFAVELL NELRAGRPFV SLVLALASIA AGLCAAGVGY
     GLGAYG