ID   CRCB2_DEIGD             Reviewed;         131 AA.
AC   Q1J3F4;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Putative fluoride ion transporter CrcB 2 {ECO:0000255|HAMAP-Rule:MF_00454};
GN   Name=crcB2 {ECO:0000255|HAMAP-Rule:MF_00454}; OrderedLocusNames=Dgeo_2546;
OS   Deinococcus geothermalis (strain DSM 11300 / AG-3a).
OG   Plasmid pDGEO01.
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=319795;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11300 / AG-3a;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Daly M.J.,
RA   Fredrickson J.K., Makarova K.S., Gaidamakova E.K., Zhai M., Richardson P.;
RT   "Complete sequence of plasmid 1 of Deinococcus geothermalis DSM 11300.";
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000255|HAMAP-Rule:MF_00454}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00454};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00454}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
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DR   EMBL; CP000358; ABF43980.1; -; Genomic_DNA.
DR   RefSeq; WP_011526017.1; NC_008010.2.
DR   AlphaFoldDB; Q1J3F4; -.
DR   SMR; Q1J3F4; -.
DR   STRING; 319795.Dgeo_2546; -.
DR   EnsemblBacteria; ABF43980; ABF43980; Dgeo_2546.
DR   KEGG; dge:Dgeo_2546; -.
DR   eggNOG; COG0239; Bacteria.
DR   HOGENOM; CLU_114342_2_3_0; -.
DR   OMA; FLMFESF; -.
DR   OrthoDB; 1942863at2; -.
DR   Proteomes; UP000002431; Plasmid pDGEO01.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR   HAMAP; MF_00454; CrcB; 1.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
DR   TIGRFAMs; TIGR00494; crcB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Plasmid; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..131
FT                   /note="Putative fluoride ion transporter CrcB 2"
FT                   /id="PRO_0000252876"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
SQ   SEQUENCE   131 AA;  13446 MW;  12D97C0D35363C48 CRC64;
     MPFWFGVAVG GALGALARYG VSLLVAGRLA STAWGNFPLA TLLVNVLGSF LLAFITTLAL
     RGLVSPAWRL AVGTGFIGAL TTFSTFAWES DLMVRDGEAA RASLYVLGNL VLGYAAVLLG
     RALAARLGGG A