CRCB2_LISMO
ID CRCB2_LISMO Reviewed; 129 AA.
AC Q8Y5I0;
DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Putative fluoride ion transporter CrcB 2 {ECO:0000255|HAMAP-Rule:MF_00454};
GN Name=crcB2 {ECO:0000255|HAMAP-Rule:MF_00454}; OrderedLocusNames=lmo2082;
OS Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=169963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-679 / EGD-e;
RX PubMed=11679669; DOI=10.1126/science.1063447;
RA Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT "Comparative genomics of Listeria species.";
RL Science 294:849-852(2001).
CC -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC thus reducing its toxicity. {ECO:0000255|HAMAP-Rule:MF_00454}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00454};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00454}.
CC -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000255|HAMAP-
CC Rule:MF_00454}.
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DR EMBL; AL591982; CAD00160.1; -; Genomic_DNA.
DR PIR; AB1335; AB1335.
DR RefSeq; NP_465606.1; NC_003210.1.
DR RefSeq; WP_003731951.1; NZ_CP023861.1.
DR AlphaFoldDB; Q8Y5I0; -.
DR SMR; Q8Y5I0; -.
DR STRING; 169963.lmo2082; -.
DR PaxDb; Q8Y5I0; -.
DR EnsemblBacteria; CAD00160; CAD00160; CAD00160.
DR GeneID; 984773; -.
DR KEGG; lmo:lmo2082; -.
DR PATRIC; fig|169963.11.peg.2132; -.
DR eggNOG; COG0239; Bacteria.
DR HOGENOM; CLU_114342_1_2_9; -.
DR OMA; EWRLFLI; -.
DR PhylomeDB; Q8Y5I0; -.
DR BioCyc; LMON169963:LMO2082-MON; -.
DR Proteomes; UP000000817; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:1903425; F:fluoride transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1903424; P:fluoride transmembrane transport; IBA:GO_Central.
DR HAMAP; MF_00454; CrcB; 1.
DR InterPro; IPR003691; CrcB.
DR PANTHER; PTHR28259; PTHR28259; 1.
DR Pfam; PF02537; CRCB; 1.
DR TIGRFAMs; TIGR00494; crcB; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..129
FT /note="Putative fluoride ion transporter CrcB 2"
FT /id="PRO_0000110130"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
SQ SEQUENCE 129 AA; 13952 MW; 6D2243529EDB1710 CRC64;
MYFLYVGVFG ALGGMCRYAM NLWLGGGDFP SATLAVNLIG CFLLAFLMRF LAEKSRVSLV
LLNGIGTGFI GAFTTFSAFS VDTIQLVQSG AWLFAVSYVL ASFIGGLIMV KFGRMLSNKL
LNRGEHRVG
