ID   CRCB_GLUOX              Reviewed;         144 AA.
AC   Q5HXN6;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Putative fluoride ion transporter CrcB {ECO:0000255|HAMAP-Rule:MF_00454};
GN   Name=crcB {ECO:0000255|HAMAP-Rule:MF_00454}; OrderedLocusNames=GOX2653;
OS   Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans).
OG   Plasmid pGOX1.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Gluconobacter.
OX   NCBI_TaxID=290633;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=621H;
RX   PubMed=15665824; DOI=10.1038/nbt1062;
RA   Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F.,
RA   Ehrenreich A., Gottschalk G., Deppenmeier U.;
RT   "Complete genome sequence of the acetic acid bacterium Gluconobacter
RT   oxydans.";
RL   Nat. Biotechnol. 23:195-200(2005).
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000255|HAMAP-Rule:MF_00454}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00454}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000004; AAW59717.1; -; Genomic_DNA.
DR   RefSeq; WP_010510921.1; NZ_LT900339.1.
DR   AlphaFoldDB; Q5HXN6; -.
DR   SMR; Q5HXN6; -.
DR   STRING; 290633.GOX2653; -.
DR   EnsemblBacteria; AAW59717; AAW59717; GOX2653.
DR   KEGG; gox:GOX2653; -.
DR   eggNOG; COG0239; Bacteria.
DR   HOGENOM; CLU_114342_3_0_5; -.
DR   OMA; TWMLETH; -.
DR   Proteomes; UP000006375; Plasmid pGOX1.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR   HAMAP; MF_00454; CrcB; 1.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
DR   TIGRFAMs; TIGR00494; crcB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Plasmid; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..144
FT                   /note="Putative fluoride ion transporter CrcB"
FT                   /id="PRO_0000110106"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
SQ   SEQUENCE   144 AA;  15144 MW;  3FE987D29CE77160 CRC64;
     MSFTTCLIVM VGGALGTLAR YLVSVAAMPI SRFIPWGTIL PINALGSFVI GFFGTLTLAD
     GRYPVSENMR LFVMIGLCGG YTTFSSFSLQ TLDLIRNDAW GRASVNVAAS VILCIGAVAL
     GHITADGFNT GAIRIAQTAT EEDA