ID   CRCB_NITMU              Reviewed;         128 AA.
AC   Q2Y8Q6;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Putative fluoride ion transporter CrcB {ECO:0000255|HAMAP-Rule:MF_00454};
GN   Name=crcB {ECO:0000255|HAMAP-Rule:MF_00454}; OrderedLocusNames=Nmul_A1562;
OS   Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=323848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25196 / NCIMB 11849 / C 71;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT   25196.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000255|HAMAP-Rule:MF_00454}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00454}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000103; ABB74865.1; -; Genomic_DNA.
DR   RefSeq; WP_011380894.1; NZ_FNVK01000015.1.
DR   AlphaFoldDB; Q2Y8Q6; -.
DR   SMR; Q2Y8Q6; -.
DR   STRING; 323848.Nmul_A1562; -.
DR   EnsemblBacteria; ABB74865; ABB74865; Nmul_A1562.
DR   KEGG; nmu:Nmul_A1562; -.
DR   eggNOG; COG0239; Bacteria.
DR   HOGENOM; CLU_114342_3_3_4; -.
DR   OMA; FLMFESF; -.
DR   OrthoDB; 1942863at2; -.
DR   Proteomes; UP000002718; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR   HAMAP; MF_00454; CrcB; 1.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
DR   TIGRFAMs; TIGR00494; crcB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..128
FT                   /note="Putative fluoride ion transporter CrcB"
FT                   /id="PRO_0000252905"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
SQ   SEQUENCE   128 AA;  13880 MW;  F2235D484335B44F CRC64;
     MGLYALTAIG AGAALGAWLR WWFGMTLNPL FPTLPLGTLA ANLTGGYLIG AAIEYFHHNS
     FLPPEARLFA ITGFLGGLTT FSTFSAETVT LLLRGQYAWT FVIIFSHLTG SLVMTILGIM
     TVKWLAQH