ID   CRCB_PROM0              Reviewed;         109 AA.
AC   A3PFC1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Putative fluoride ion transporter CrcB;
GN   Name=crcB; OrderedLocusNames=P9301_18231;
OS   Prochlorococcus marinus (strain MIT 9301).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=167546;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIT 9301;
RX   PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA   Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA   Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA   Richardson P., Chisholm S.W.;
RT   "Patterns and implications of gene gain and loss in the evolution of
RT   Prochlorococcus.";
RL   PLoS Genet. 3:2515-2528(2007).
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000305}.
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DR   EMBL; CP000576; ABO18446.1; -; Genomic_DNA.
DR   RefSeq; WP_011863731.1; NC_009091.1.
DR   AlphaFoldDB; A3PFC1; -.
DR   SMR; A3PFC1; -.
DR   STRING; 167546.P9301_18231; -.
DR   EnsemblBacteria; ABO18446; ABO18446; P9301_18231.
DR   KEGG; pmg:P9301_18231; -.
DR   HOGENOM; CLU_2181556_0_0_3; -.
DR   OMA; WISRKIT; -.
DR   Proteomes; UP000001430; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR003691; CrcB.
DR   Pfam; PF02537; CRCB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..109
FT                   /note="Putative fluoride ion transporter CrcB"
FT                   /id="PRO_1000026406"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   109 AA;  12937 MW;  4CCB0D9BE2C7CF2A CRC64;
     MKINNFIYIF LAAYLATFFR LTLNNNFFIS IIGSFLVGFF VSKRLSYSNE KILFSGFFSC
     FTSFSGFIYF LYKILNQGDW IKFIIFFNLI IILNLLTMIF GFWISRKIT