CRCB_PSEYM
ID CRCB_PSEYM Reviewed; 127 AA.
AC Q93TE2;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Putative fluoride ion transporter CrcB {ECO:0000255|HAMAP-Rule:MF_00454};
GN Name=crcB {ECO:0000255|HAMAP-Rule:MF_00454};
OS Pseudomonas syringae pv. maculicola.
OG Plasmid pFKN.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=59511;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=M6;
RX PubMed=12622811; DOI=10.1046/j.1365-2958.2003.03402.x;
RA Rohmer L., Kjemtrup S., Marchesini P., Dangl J.L.;
RT "Nucleotide sequence, functional characterization and evolution of pFKN, a
RT virulence plasmid in Pseudomonas syringae pathovar maculicola.";
RL Mol. Microbiol. 47:1545-1562(2003).
CC -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC thus reducing its toxicity. {ECO:0000255|HAMAP-Rule:MF_00454}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00454}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00454}.
CC -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000255|HAMAP-
CC Rule:MF_00454}.
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DR EMBL; AF359557; AAK49548.1; -; Genomic_DNA.
DR RefSeq; NP_114206.1; NC_002759.1.
DR RefSeq; WP_010924788.1; NZ_LJQR01000061.1.
DR AlphaFoldDB; Q93TE2; -.
DR SMR; Q93TE2; -.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:1903425; F:fluoride transmembrane transporter activity; IEA:UniProt.
DR HAMAP; MF_00454; CrcB; 1.
DR InterPro; IPR003691; CrcB.
DR PANTHER; PTHR28259; PTHR28259; 1.
DR Pfam; PF02537; CRCB; 1.
DR TIGRFAMs; TIGR00494; crcB; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Plasmid; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..127
FT /note="Putative fluoride ion transporter CrcB"
FT /id="PRO_0000110160"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00454"
SQ SEQUENCE 127 AA; 13291 MW; EC0A9C99C5F71E93 CRC64;
MLKSLLVIAI GASLGAWLRW LLGMKLNALF PTIPPGTVVA NMVGGYIIGL AIAFLAASPS
LSPEWRLLII TGFCGGLTTF STFSAETVAL IQEGRLLWAL GSISLHVVGS LAMTAAGLLS
YQMIGTR