ID   CREG1_CHICK             Reviewed;         192 AA.
AC   Q5ZJ73;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Protein CREG1;
DE   Flags: Precursor;
GN   Name=CREG1; ORFNames=RCJMB04_20e8;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May contribute to the transcriptional control of cell growth
CC       and differentiation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CREG family. {ECO:0000305}.
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DR   EMBL; AJ720561; CAG32220.1; -; mRNA.
DR   RefSeq; NP_001291993.1; NM_001305064.1.
DR   AlphaFoldDB; Q5ZJ73; -.
DR   SMR; Q5ZJ73; -.
DR   STRING; 9031.ENSGALP00000043319; -.
DR   Ensembl; ENSGALT00000089070; ENSGALP00000063324; ENSGALG00000040426.
DR   GeneID; 768680; -.
DR   KEGG; gga:768680; -.
DR   CTD; 8804; -.
DR   VEuPathDB; HostDB:geneid_768680; -.
DR   eggNOG; KOG3374; Eukaryota.
DR   GeneTree; ENSGT00390000005914; -.
DR   HOGENOM; CLU_083635_3_1_1; -.
DR   InParanoid; Q5ZJ73; -.
DR   OMA; CAHIIFV; -.
DR   OrthoDB; 1252017at2759; -.
DR   PhylomeDB; Q5ZJ73; -.
DR   Reactome; R-GGA-6798695; Neutrophil degranulation.
DR   PRO; PR:Q5ZJ73; -.
DR   Proteomes; UP000000539; Chromosome 1.
DR   Bgee; ENSGALG00000040426; Expressed in lung and 14 other tissues.
DR   ExpressionAtlas; Q5ZJ73; baseline and differential.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.110.10; -; 1.
DR   InterPro; IPR014631; CREG.
DR   InterPro; IPR012349; Split_barrel_FMN-bd.
DR   PIRSF; PIRSF036911; CREG; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Growth regulation; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..192
FT                   /note="Protein CREG1"
FT                   /id="PRO_0000006205"
FT   CARBOHYD        95
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        133
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        166
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   192 AA;  21106 MW;  3C952C43068DFFFB CRC64;
     MVLLAFLCAA ALAALARGTI PPPEEAARMA RFVLHNCDWG ALATLSAQEG LRGRPFANIF
     SISDGAPGPG GGSGVPYLYL TDMEISVQDL EVNSNASLTV SLAQTPYCKK HRYDPQNPLC
     AHIIFCGSIV KVNDSEAALA KKALFTRHPE MESWPKDHNW FYAKFNITNI WVLDYFGGLK
     IVTPEEYYNV KP