CREN7_SACSH
ID CREN7_SACSH Reviewed; 60 AA.
AC P0C835;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-JUL-2008, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Chromatin protein Cren7;
GN Name=cren7;
OS Saccharolobus shibatae (Sulfolobus shibatae).
OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Saccharolobus.
OX NCBI_TaxID=2286;
RN [1]
RP PROTEIN SEQUENCE, METHYLATION AT LYS-16, SUBUNIT, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RC STRAIN=ATCC 51178 / DSM 5389 / JCM 8931 / NBRC 15437 / B12;
RX PubMed=18096617; DOI=10.1093/nar/gkm1128;
RA Guo L., Feng Y., Zhang Z., Yao H., Luo Y., Wang J., Huang L.;
RT "Biochemical and structural characterization of Cren7, a novel chromatin
RT protein conserved among Crenarchaea.";
RL Nucleic Acids Res. 36:1129-1137(2008).
CC -!- FUNCTION: A probable chromatin protein, binds double-strand DNA without
CC sequence specificity. Constrains negative DNA supercoils (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:18096617}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- PTM: Methylated at multiple sites, to varying extents. At least one
CC methylation occurs on Lys-16. {ECO:0000269|PubMed:18096617}.
CC -!- SIMILARITY: Belongs to the Cren7 family. {ECO:0000305}.
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DR RefSeq; WP_012711256.1; NZ_CP077715.1.
DR AlphaFoldDB; P0C835; -.
DR SMR; P0C835; -.
DR iPTMnet; P0C835; -.
DR GeneID; 8761176; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 2.30.30.610; -; 1.
DR HAMAP; MF_01387; Chromatin_Cren7; 1.
DR InterPro; IPR038647; Cren7_sf.
DR InterPro; IPR020906; dsDNA-bd_Cren7.
DR Pfam; PF11520; Cren7; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Direct protein sequencing; DNA-binding; Methylation.
FT INIT_MET 1
FT /note="Removed"
FT CHAIN 2..60
FT /note="Chromatin protein Cren7"
FT /id="PRO_0000345177"
FT MOD_RES 16
FT /note="N6-methyllysine"
FT /evidence="ECO:0000269|PubMed:18096617"
SQ SEQUENCE 60 AA; 6637 MW; 874AC5BE3FB897E0 CRC64;
MSSGKKAVKV KTPAGKEAEL VPEKVWALAP KGRKGVKIGL FKDPETGKYF RHKLPDDYPI