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CRGC_MACMU
ID   CRGC_MACMU              Reviewed;         174 AA.
AC   A3RLD8;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Gamma-crystallin C;
DE   AltName: Full=Gamma-C-crystallin;
GN   Name=CRYGC;
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Lens;
RA   Wistow G.;
RT   "Rhesus monkey gammaC-crystallin.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Crystallins are the dominant structural components of the
CC       vertebrate eye lens. {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- DOMAIN: Has a two-domain beta-structure, folded into four very similar
CC       Greek key motifs.
CC   -!- SIMILARITY: Belongs to the beta/gamma-crystallin family. {ECO:0000305}.
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DR   EMBL; EF426305; ABO14690.1; -; mRNA.
DR   RefSeq; NP_001076433.1; NM_001082964.1.
DR   AlphaFoldDB; A3RLD8; -.
DR   SMR; A3RLD8; -.
DR   STRING; 9544.ENSMMUP00000015388; -.
DR   Ensembl; ENSMMUT00000087819; ENSMMUP00000070892; ENSMMUG00000056938.
DR   GeneID; 709553; -.
DR   KEGG; mcc:709553; -.
DR   CTD; 1420; -.
DR   VEuPathDB; HostDB:ENSMMUG00000056938; -.
DR   eggNOG; ENOG502RXJY; Eukaryota.
DR   GeneTree; ENSGT00940000159232; -.
DR   HOGENOM; CLU_081883_1_1_1; -.
DR   InParanoid; A3RLD8; -.
DR   OMA; YEREEYK; -.
DR   Proteomes; UP000006718; Chromosome 12.
DR   Bgee; ENSMMUG00000056938; Expressed in liver and 2 other tissues.
DR   ExpressionAtlas; A3RLD8; baseline.
DR   GO; GO:0005212; F:structural constituent of eye lens; IBA:GO_Central.
DR   GO; GO:0002088; P:lens development in camera-type eye; IBA:GO_Central.
DR   GO; GO:0007601; P:visual perception; IBA:GO_Central.
DR   InterPro; IPR001064; Beta/gamma_crystallin.
DR   InterPro; IPR011024; G_crystallin-like.
DR   Pfam; PF00030; Crystall; 2.
DR   PRINTS; PR01367; BGCRYSTALLIN.
DR   SMART; SM00247; XTALbg; 2.
DR   SUPFAM; SSF49695; SSF49695; 1.
DR   PROSITE; PS50915; CRYSTALLIN_BETA_GAMMA; 4.
PE   2: Evidence at transcript level;
KW   Eye lens protein; Methylation; Reference proteome; Repeat.
FT   CHAIN           1..174
FT                   /note="Gamma-crystallin C"
FT                   /id="PRO_0000289609"
FT   DOMAIN          2..40
FT                   /note="Beta/gamma crystallin 'Greek key' 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00028"
FT   DOMAIN          41..83
FT                   /note="Beta/gamma crystallin 'Greek key' 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00028"
FT   DOMAIN          88..128
FT                   /note="Beta/gamma crystallin 'Greek key' 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00028"
FT   DOMAIN          129..171
FT                   /note="Beta/gamma crystallin 'Greek key' 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00028"
FT   REGION          84..87
FT                   /note="Connecting peptide"
FT   MOD_RES         23
FT                   /note="S-methylcysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   174 AA;  20730 MW;  4D50B9AE32B09CC5 CRC64;
     MGKITLYEDK AFQGRSYEST TDCPNLQTYL SRCNSIRVES GCWMLYERPN YQGQQYLLRR
     GEYPDYQQWM GLSDSIRSCC LIPQTGSHRL RLYEREDHKG LMMELSEDCP SIQDRFHLSE
     IRSLHVLEGC WVLYELPNYR GRQYLLRPQE YRRCQDWGAM DAKAGSLRRV VDLY
 
 
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