CRIM2_ARATH
ID CRIM2_ARATH Reviewed; 226 AA.
AC F4I1G5; F4I1G6; Q8L813; Q8RXM0;
DT 28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Cold-regulated 413 inner membrane protein 2, chloroplastic;
DE Short=AtCOR413-IM2;
DE AltName: Full=Cold-regulated 413 thylakoid membrane 2;
DE Short=AtCOR413-TM2;
DE Flags: Precursor;
GN Name=COR413IM2; Synonyms=COR314TM2, COR413TM2; OrderedLocusNames=At1g29390;
GN ORFNames=F15D2.42;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 8-226 (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12746512; DOI=10.1104/pp.102.015255;
RA Breton G., Danyluk J., Charron J.-B.F., Sarhan F.;
RT "Expression profiling and bioinformatic analyses of a novel stress-
RT regulated multispanning transmembrane protein family from cereals and
RT Arabidopsis.";
RL Plant Physiol. 132:64-74(2003).
RN [5]
RP TRANSIT PEPTIDE CLEAVAGE SITE, SUBCELLULAR LOCATION, TOPOLOGY, AND
RP INDUCTION BY COLD.
RX PubMed=18643950; DOI=10.1111/j.1365-3040.2008.01854.x;
RA Okawa K., Nakayama K., Kakizaki T., Yamashita T., Inaba T.;
RT "Identification and characterization of Cor413im proteins as novel
RT components of the chloroplast inner envelope.";
RL Plant Cell Environ. 31:1470-1483(2008).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RX PubMed=18431481; DOI=10.1371/journal.pone.0001994;
RA Zybailov B., Rutschow H., Friso G., Rudella A., Emanuelsson O., Sun Q.,
RA van Wijk K.J.;
RT "Sorting signals, N-terminal modifications and abundance of the chloroplast
RT proteome.";
RL PLoS ONE 3:E1994-E1994(2008).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000269|PubMed:18431481, ECO:0000269|PubMed:18643950}; Multi-pass
CC membrane protein {ECO:0000269|PubMed:18431481,
CC ECO:0000269|PubMed:18643950}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=F4I1G5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=F4I1G5-2; Sequence=VSP_044490;
CC -!- INDUCTION: Accumulates at low levels in response to cold treatment.
CC {ECO:0000269|PubMed:18643950}.
CC -!- SIMILARITY: Belongs to the Cold-regulated 413 protein family.
CC {ECO:0000305}.
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DR EMBL; AC068667; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE31079.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31080.1; -; Genomic_DNA.
DR EMBL; AY080813; AAL87293.1; -; mRNA.
DR EMBL; AY123008; AAM67541.1; -; mRNA.
DR RefSeq; NP_564327.1; NM_102678.3. [F4I1G5-1]
DR RefSeq; NP_973936.1; NM_202207.1. [F4I1G5-2]
DR AlphaFoldDB; F4I1G5; -.
DR BioGRID; 25049; 12.
DR IntAct; F4I1G5; 12.
DR STRING; 3702.AT1G29390.1; -.
DR PaxDb; F4I1G5; -.
DR PRIDE; F4I1G5; -.
DR EnsemblPlants; AT1G29390.1; AT1G29390.1; AT1G29390. [F4I1G5-1]
DR EnsemblPlants; AT1G29390.2; AT1G29390.2; AT1G29390. [F4I1G5-2]
DR GeneID; 839814; -.
DR Gramene; AT1G29390.1; AT1G29390.1; AT1G29390. [F4I1G5-1]
DR Gramene; AT1G29390.2; AT1G29390.2; AT1G29390. [F4I1G5-2]
DR KEGG; ath:AT1G29390; -.
DR Araport; AT1G29390; -.
DR TAIR; locus:2013743; AT1G29390.
DR eggNOG; ENOG502RXZY; Eukaryota.
DR InParanoid; F4I1G5; -.
DR OMA; CITAVSC; -.
DR PRO; PR:F4I1G5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I1G5; baseline and differential.
DR Genevisible; F4I1G5; AT.
DR GO; GO:0009941; C:chloroplast envelope; IDA:TAIR.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.
DR GO; GO:0031357; C:integral component of chloroplast inner membrane; IDA:TAIR.
DR GO; GO:0070417; P:cellular response to cold; IEP:TAIR.
DR GO; GO:0009631; P:cold acclimation; IMP:TAIR.
DR InterPro; IPR008892; COR413.
DR PANTHER; PTHR33596; PTHR33596; 1.
DR Pfam; PF05562; WCOR413; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Chloroplast; Membrane; Plastid;
KW Plastid inner membrane; Reference proteome; Transit peptide; Transmembrane;
KW Transmembrane helix.
FT TRANSIT 1..76
FT /note="Chloroplast"
FT /evidence="ECO:0000305|PubMed:18643950"
FT CHAIN 77..226
FT /note="Cold-regulated 413 inner membrane protein 2,
FT chloroplastic"
FT /id="PRO_0000420445"
FT TOPO_DOM 77..79
FT /note="Stromal"
FT /evidence="ECO:0000255"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 101..103
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 125..129
FT /note="Stromal"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 151..152
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 153..173
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 174..176
FT /note="Stromal"
FT /evidence="ECO:0000255"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 198..205
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255"
FT VAR_SEQ 1..47
FT /note="MASLCLSSSRIVSLHHQKPFLALKLRPRPSNISGLGHSTSVVCFNPL -> M
FT LVG (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_044490"
SQ SEQUENCE 226 AA; 24798 MW; 05FCF00E2CF4B439 CRC64;
MASLCLSSSR IVSLHHQKPF LALKLRPRPS NISGLGHSTS VVCFNPLRLS ADRQRTATVS
ARAEKRRKRG SSVVCYATPM LSVHNLQWIS TISCVALMFA RGTGIHKSFV VPLFALQAPM
GIVSWMKGEY GIWAAFLALL TRLFFSFPVE LELPFIALLL VIVAPYQVMS IRGKQEGAIL
SLAISCFLAF QHFSRAGTLQ KAFDQNSVLA TVAIIGVTVV SFLFLI
