ID   CRIP1_BOVIN             Reviewed;          77 AA.
AC   Q56K04;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Cysteine-rich protein 1;
DE            Short=CRP-1;
GN   Name=CRIP1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lymphoid epithelium;
RA   Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.;
RT   "Analysis of sequences obtained from constructed full-length bovine cDNA
RT   libraries.";
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Seems to have a role in zinc absorption and may function as
CC       an intracellular zinc transport protein. {ECO:0000250}.
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DR   EMBL; AY911323; AAW82091.1; -; mRNA.
DR   EMBL; BC102754; AAI02755.1; -; mRNA.
DR   RefSeq; NP_001020520.1; NM_001025349.2.
DR   AlphaFoldDB; Q56K04; -.
DR   SMR; Q56K04; -.
DR   STRING; 9913.ENSBTAP00000054703; -.
DR   PaxDb; Q56K04; -.
DR   PRIDE; Q56K04; -.
DR   GeneID; 574093; -.
DR   KEGG; bta:574093; -.
DR   CTD; 1396; -.
DR   eggNOG; KOG1700; Eukaryota.
DR   HOGENOM; CLU_026811_4_1_1; -.
DR   InParanoid; Q56K04; -.
DR   OrthoDB; 1214165at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071236; P:cellular response to antibiotic; ISS:UniProtKB.
DR   GO; GO:0071493; P:cellular response to UV-B; ISS:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; ISS:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   GO; GO:0010043; P:response to zinc ion; ISS:UniProtKB.
DR   InterPro; IPR001781; Znf_LIM.
DR   Pfam; PF00412; LIM; 1.
DR   SMART; SM00132; LIM; 1.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE   3: Inferred from homology;
KW   Acetylation; LIM domain; Metal-binding; Methylation; Reference proteome;
KW   Zinc.
FT   CHAIN           1..77
FT                   /note="Cysteine-rich protein 1"
FT                   /id="PRO_0000075706"
FT   DOMAIN          2..63
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   MOD_RES         9
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P50238"
FT   MOD_RES         22
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P63254"
FT   MOD_RES         68
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0000250|UniProtKB:P63254"
SQ   SEQUENCE   77 AA;  8506 MW;  A9716A6418CA21D1 CRC64;
     MPKCPKCSKE VYFAERVTSL GKDWHRPCLK CEKCGKTLTS GGHAEHEGKP YCNHPCYAAM
     FGPKGFGRGG AESHTFK