ID   CRL_ENT38               Reviewed;         133 AA.
AC   A4W6X2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Sigma factor-binding protein Crl {ECO:0000255|HAMAP-Rule:MF_01178};
GN   Name=crl {ECO:0000255|HAMAP-Rule:MF_01178}; OrderedLocusNames=Ent638_0766;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638;
RX   PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA   Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA   Vangronsveld J., Newman L., Monchy S.;
RT   "Genome sequence of the plant growth promoting endophytic bacterium
RT   Enterobacter sp. 638.";
RL   PLoS Genet. 6:E1000943-E1000943(2010).
CC   -!- FUNCTION: Binds to the sigma-S subunit of RNA polymerase, activating
CC       expression of sigma-S-regulated genes. Stimulates RNA polymerase
CC       holoenzyme formation and may bind to several other sigma factors, such
CC       as sigma-70 and sigma-32. {ECO:0000255|HAMAP-Rule:MF_01178}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01178}.
CC   -!- SIMILARITY: Belongs to the Crl family. {ECO:0000255|HAMAP-
CC       Rule:MF_01178}.
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DR   EMBL; CP000653; ABP59452.1; -; Genomic_DNA.
DR   RefSeq; WP_012016173.1; NC_009436.1.
DR   AlphaFoldDB; A4W6X2; -.
DR   SMR; A4W6X2; -.
DR   STRING; 399742.Ent638_0766; -.
DR   EnsemblBacteria; ABP59452; ABP59452; Ent638_0766.
DR   KEGG; ent:Ent638_0766; -.
DR   eggNOG; ENOG502ZQ8E; Bacteria.
DR   HOGENOM; CLU_136773_0_0_6; -.
DR   OMA; FWGWWLE; -.
DR   OrthoDB; 1914214at2; -.
DR   Proteomes; UP000000230; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.310.230; -; 1.
DR   HAMAP; MF_01178; Crl; 1.
DR   InterPro; IPR009986; Tscrpt_reg_Crl.
DR   InterPro; IPR038208; Tscrpt_reg_Crl_sf.
DR   Pfam; PF07417; Crl; 1.
PE   3: Inferred from homology;
KW   Activator; Coiled coil; Cytoplasm; Transcription; Transcription regulation.
FT   CHAIN           1..133
FT                   /note="Sigma factor-binding protein Crl"
FT                   /id="PRO_1000065787"
FT   REGION          99..122
FT                   /note="Essential for activity"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01178"
FT   COILED          90..113
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01178"
SQ   SEQUENCE   133 AA;  15808 MW;  B71DECCEB6E12DDF CRC64;
     MTLPSGHPKS RLIKKFMALG PYIREEQCEE NRFFFDCLAV CVNVQPAPEE REFWGWWMEM
     EAEEKRFTYT YHFGLFNKAG HWQATTIKDK EVVERLEQTL RGFHEKARAL LETFELKLEP
     ADDFTNEKLK LSA