ID   CROB_LEPLU              Reviewed;          89 AA.
AC   P49261;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Rho beta-crystallin;
DE   Flags: Fragments;
OS   Lepidodactylus lugubris (Mourning gecko).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Gekkota; Gekkonidae; Gekkoninae;
OC   Lepidodactylus.
OX   NCBI_TaxID=47724;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Lens;
RX   PubMed=7503721; DOI=10.1006/bbrc.1995.2797;
RA   Roell B., van Boekel M.A.M., Amons R., de Jong W.W.;
RT   "Rho B-crystallin, an aldose reductase-like lens protein in the gecko
RT   Lepidodactylus lugubris.";
RL   Biochem. Biophys. Res. Commun. 217:452-458(1995).
CC   -!- SUBUNIT: Monomer.
CC   -!- SIMILARITY: Belongs to the aldo/keto reductase family. {ECO:0000305}.
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DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.100; -; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   PRINTS; PR00069; ALDKETRDTASE.
DR   SUPFAM; SSF51430; SSF51430; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Eye lens protein.
FT   CHAIN           1..89
FT                   /note="Rho beta-crystallin"
FT                   /id="PRO_0000124615"
FT   BINDING         31
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   NON_CONS        31..32
FT                   /evidence="ECO:0000305"
FT   NON_CONS        37..38
FT                   /evidence="ECO:0000305"
FT   NON_CONS        62..63
FT                   /evidence="ECO:0000305"
FT   NON_CONS        81..82
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   89 AA;  10228 MW;  8BADB793712F5834 CRC64;
     MPILGLGTWQ APPGKVEKAI KLDYLDLYLI HFPMGFKVIP SNTDIRDTWE GMEDLVDAGL
     VKYTSLIEDP XVKKIADKYN KEYPFHVDY