CRR6_ARATH
ID CRR6_ARATH Reviewed; 246 AA.
AC O82258;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=Protein CHLORORESPIRATORY REDUCTION 6, chloroplastic {ECO:0000305};
DE Flags: Precursor;
GN Name=CRR6 {ECO:0000303|PubMed:16648216};
GN OrderedLocusNames=At2g47910 {ECO:0000312|Araport:AT2G47910};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=16648216; DOI=10.1104/pp.106.080267;
RA Munshi M.K., Kobayashi Y., Shikanai T.;
RT "Chlororespiratory reduction 6 is a novel factor required for accumulation
RT of the chloroplast NAD(P)H dehydrogenase complex in Arabidopsis.";
RL Plant Physiol. 141:737-744(2006).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=20444231; DOI=10.1111/j.1365-313x.2010.04240.x;
RA Peng L., Cai W., Shikanai T.;
RT "Chloroplast stromal proteins, CRR6 and CRR7, are required for assembly of
RT the NAD(P)H dehydrogenase subcomplex A in Arabidopsis.";
RL Plant J. 63:203-211(2010).
CC -!- FUNCTION: Required for both formation and activity of the chloroplast
CC NAD(P)H dehydrogenase (NDH) complex of the photosynthetic electron
CC transport chain. May function in assembly or stabilization of the NDH
CC complex (PubMed:16648216, PubMed:20444231). Required for the
CC accumulation of NDH subcomplex A, which is a core part of NDH. May be
CC involved in post-translational steps during the biogenesis of
CC subcomplex A (PubMed:20444231). {ECO:0000269|PubMed:16648216,
CC ECO:0000269|PubMed:20444231}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC {ECO:0000269|PubMed:20444231}. Note=Previously localized in chloroplast
CC thylakoid membrane fraction. {ECO:0000269|PubMed:16648216}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences. {ECO:0000305};
CC Name=1;
CC IsoId=O82258-1; Sequence=Displayed;
CC -!- DISRUPTION PHENOTYPE: Impaired chloroplastic NAD(P)H dehydrogenase
CC (NDH) activity, probably due to a reduced stability of the NDH complex.
CC {ECO:0000269|PubMed:16648216, ECO:0000269|PubMed:20444231}.
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DR EMBL; AC005309; AAC63645.1; -; Genomic_DNA.
DR EMBL; AC006072; AAM15131.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10910.1; -; Genomic_DNA.
DR EMBL; AF324707; AAG40058.1; -; mRNA.
DR EMBL; AF339704; AAK00386.1; -; mRNA.
DR EMBL; AY045692; AAK74050.1; -; mRNA.
DR EMBL; AY054146; AAL06807.1; -; mRNA.
DR EMBL; AY084309; AAM60898.1; -; mRNA.
DR PIR; A84921; A84921.
DR RefSeq; NP_566113.1; NM_130358.4. [O82258-1]
DR AlphaFoldDB; O82258; -.
DR STRING; 3702.AT2G47910.1; -.
DR iPTMnet; O82258; -.
DR PaxDb; O82258; -.
DR PRIDE; O82258; -.
DR ProteomicsDB; 222645; -. [O82258-1]
DR EnsemblPlants; AT2G47910.1; AT2G47910.1; AT2G47910. [O82258-1]
DR GeneID; 819403; -.
DR Gramene; AT2G47910.1; AT2G47910.1; AT2G47910. [O82258-1]
DR KEGG; ath:AT2G47910; -.
DR Araport; AT2G47910; -.
DR TAIR; locus:2043338; AT2G47910.
DR eggNOG; ENOG502QTFV; Eukaryota.
DR HOGENOM; CLU_092224_0_0_1; -.
DR InParanoid; O82258; -.
DR PhylomeDB; O82258; -.
DR PRO; PR:O82258; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O82258; baseline and differential.
DR Genevisible; O82258; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0009570; C:chloroplast stroma; IDA:TAIR.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0010275; P:NAD(P)H dehydrogenase complex assembly; IMP:TAIR.
DR InterPro; IPR014946; CRR6.
DR PANTHER; PTHR35724; PTHR35724; 1.
DR Pfam; PF08847; Crr6; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Chaperone; Chloroplast; Plastid; Reference proteome;
KW Transit peptide.
FT TRANSIT 1..59
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 60..246
FT /note="Protein CHLORORESPIRATORY REDUCTION 6,
FT chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_0000433243"
SQ SEQUENCE 246 AA; 28028 MW; 98BB8336C223F3C9 CRC64;
MATKAVLLPW LIPSPRHVSL FPVVQLPALE TAGWCVRKRR AEDVAVSVAF NPSGNFDISA
FENDQDSDKV EPPMPPTTGR YEVVIDNDSI GRLDLSPFQR AIGITSPDDF GVAEPKRYLD
RTIGFTINYK REDPGDPREL SEYPDVRLWF VRLDAMYPWL PLLLDWRAGE LARYAAMLVP
HQMSLRMGVV FNPEALELFV MNKVFVVYPW LKRHGVPKPR LKTSDMARML GFGIGDELFD
LIDHNE
