CRRS1_ARATH
ID CRRS1_ARATH Reviewed; 341 AA.
AC Q9SYB1; F4HVF3;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 22-FEB-2012, sequence version 3.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Cysteine-rich repeat secretory protein 1;
DE Flags: Precursor;
GN Name=CRRSP1; OrderedLocusNames=At1g61750; ORFNames=T13M11.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=11402176; DOI=10.1104/pp.126.2.473;
RA Chen Z.;
RT "A superfamily of proteins with novel cysteine-rich repeats.";
RL Plant Physiol. 126:473-476(2001).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cysteine-rich repeat secretory protein
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD21420.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC005882; AAD21420.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33882.1; -; Genomic_DNA.
DR PIR; C96643; C96643.
DR RefSeq; NP_176368.4; NM_104857.5.
DR AlphaFoldDB; Q9SYB1; -.
DR SMR; Q9SYB1; -.
DR iPTMnet; Q9SYB1; -.
DR PaxDb; Q9SYB1; -.
DR PRIDE; Q9SYB1; -.
DR ProteomicsDB; 222682; -.
DR EnsemblPlants; AT1G61750.1; AT1G61750.1; AT1G61750.
DR GeneID; 842472; -.
DR Gramene; AT1G61750.1; AT1G61750.1; AT1G61750.
DR KEGG; ath:AT1G61750; -.
DR Araport; AT1G61750; -.
DR TAIR; locus:2195778; AT1G61750.
DR eggNOG; ENOG502QWDY; Eukaryota.
DR HOGENOM; CLU_000288_35_0_1; -.
DR InParanoid; Q9SYB1; -.
DR OMA; TVEYRMD; -.
DR OrthoDB; 1216944at2759; -.
DR PRO; PR:Q9SYB1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SYB1; baseline and differential.
DR Genevisible; Q9SYB1; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.430.20; -; 2.
DR InterPro; IPR002902; GNK2.
DR InterPro; IPR038408; GNK2_sf.
DR Pfam; PF01657; Stress-antifung; 2.
DR PROSITE; PS51473; GNK2; 2.
PE 3: Inferred from homology;
KW Disulfide bond; Reference proteome; Repeat; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..341
FT /note="Cysteine-rich repeat secretory protein 1"
FT /id="PRO_0000296129"
FT DOMAIN 28..131
FT /note="Gnk2-homologous 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
FT DOMAIN 136..245
FT /note="Gnk2-homologous 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
FT REGION 247..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..265
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 85..94
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
FT DISULFID 97..122
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
FT DISULFID 199..208
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
FT DISULFID 211..236
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
SQ SEQUENCE 341 AA; 38617 MW; 86A9EE383D818A3D CRC64;
MFSLPLHQSK LIFLLSFLLI KTLNAQPTYL LSYCYTSGNY TPNSSYKSNL DTLISVLDSQ
SSNKGFYSYA SGSSPTTTVY GSYLCRGDIS SSTCETCISR ASKNVFIWCP VQKEAIIWYE
ECFLRYSSRK IFSILDQGPF VTWTSYDTTL YQFYFINTVE YRMDRLIQEA YSSSSYFAEE
TYHVSYLGEV YDLNGLVQCT PDLNQYDCYR CLKSAYNETK DCCYGKRFAL VYSSNCMLTY
KATFLAPPPP PPPPPPPPPP PQRLYGENDT PSSDESFSFK LGKVFRRIIA PVIAAVVIIL
VISVCSLCCC CIKKKKKANQ REASIEIPTL NTGENLTVDH Q
