ID   CRRS6_ARATH             Reviewed;         273 AA.
AC   Q9SH42;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Probable cysteine-rich repeat secretory protein 6;
DE   Flags: Precursor;
GN   Name=CRRSP6; OrderedLocusNames=At1g63580; ORFNames=F2K11.6;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX   PubMed=11402176; DOI=10.1104/pp.126.2.473;
RA   Chen Z.;
RT   "A superfamily of proteins with novel cysteine-rich repeats.";
RL   Plant Physiol. 126:473-476(2001).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cysteine-rich repeat secretory protein
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF19717.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC008047; AAF19717.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE34115.1; -; Genomic_DNA.
DR   PIR; H96660; H96660.
DR   RefSeq; NP_176546.1; NM_105036.2.
DR   AlphaFoldDB; Q9SH42; -.
DR   SMR; Q9SH42; -.
DR   BioGRID; 27884; 1.
DR   IntAct; Q9SH42; 1.
DR   STRING; 3702.AT1G63580.1; -.
DR   PaxDb; Q9SH42; -.
DR   PRIDE; Q9SH42; -.
DR   ProteomicsDB; 224527; -.
DR   EnsemblPlants; AT1G63580.1; AT1G63580.1; AT1G63580.
DR   GeneID; 842663; -.
DR   Gramene; AT1G63580.1; AT1G63580.1; AT1G63580.
DR   KEGG; ath:AT1G63580; -.
DR   Araport; AT1G63580; -.
DR   TAIR; locus:2031295; AT1G63580.
DR   eggNOG; ENOG502QWDY; Eukaryota.
DR   HOGENOM; CLU_000288_35_0_1; -.
DR   InParanoid; Q9SH42; -.
DR   OMA; FIFYDEC; -.
DR   OrthoDB; 1194995at2759; -.
DR   PhylomeDB; Q9SH42; -.
DR   PRO; PR:Q9SH42; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9SH42; baseline and differential.
DR   Genevisible; Q9SH42; AT.
DR   GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR   Gene3D; 3.30.430.20; -; 2.
DR   InterPro; IPR002902; GNK2.
DR   InterPro; IPR038408; GNK2_sf.
DR   Pfam; PF01657; Stress-antifung; 2.
DR   PROSITE; PS51473; GNK2; 2.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..273
FT                   /note="Probable cysteine-rich repeat secretory protein 6"
FT                   /id="PRO_0000296134"
FT   DOMAIN          22..122
FT                   /note="Gnk2-homologous 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
FT   DOMAIN          128..241
FT                   /note="Gnk2-homologous 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
SQ   SEQUENCE   273 AA;  30350 MW;  AA825E9DD10851C5 CRC64;
     MTRIIDVSLF CFFLFSLGAM SQPSQNLTDC NQFPDTYQSN RNTVLSTLRN HSSLGSYYFN
     ATAGLSPNTV YGMFLCIGNI SKTSCSNCVH SATLEMDKSC ESHDTSFMFS DECMVRYSDN
     SFFSLVEDSP ATFSYSQNDS LSYPQFYNQT LPGKLDELIL KAPSSFSSPV PYFVEDKEHV
     TQVEGSYDLE AMAQCSPDLD PSSCTVCLGL VVEKFSECCS QSRWARIHFP KCLLRYDISA
     LQPNLTSLGV TTKGDDIFGR TFIAIMIGLL MGL