ID   CRRS8_ARATH             Reviewed;         284 AA.
AC   Q9SH40; F4I3N0; Q6NPE1;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Cysteine-rich repeat secretory protein 8;
DE   Flags: Precursor;
GN   Name=CRRSP8; OrderedLocusNames=At1g63560; ORFNames=F2K11.8;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4-284.
RC   STRAIN=cv. Columbia;
RA   Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT   "Arabidopsis cDNA clones.";
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX   PubMed=11402176; DOI=10.1104/pp.126.2.473;
RA   Chen Z.;
RT   "A superfamily of proteins with novel cysteine-rich repeats.";
RL   Plant Physiol. 126:473-476(2001).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cysteine-rich repeat secretory protein
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAR20768.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=AAR24761.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC008047; AAF19715.1; -; Genomic_DNA.
DR   EMBL; CP002684; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BT010711; AAR20768.2; ALT_INIT; mRNA.
DR   EMBL; BT010983; AAR24761.1; ALT_INIT; mRNA.
DR   PIR; G96660; G96660.
DR   AlphaFoldDB; Q9SH40; -.
DR   SMR; Q9SH40; -.
DR   PaxDb; Q9SH40; -.
DR   PRIDE; Q9SH40; -.
DR   Araport; AT1G63560; -.
DR   HOGENOM; CLU_000288_35_0_1; -.
DR   InParanoid; Q9SH40; -.
DR   PhylomeDB; Q9SH40; -.
DR   PRO; PR:Q9SH40; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9SH40; baseline and differential.
DR   Genevisible; Q9SH40; AT.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.430.20; -; 2.
DR   InterPro; IPR002902; GNK2.
DR   InterPro; IPR038408; GNK2_sf.
DR   Pfam; PF01657; Stress-antifung; 2.
DR   PROSITE; PS51473; GNK2; 2.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; Secreted; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..284
FT                   /note="Cysteine-rich repeat secretory protein 8"
FT                   /id="PRO_0000296136"
FT   DOMAIN          32..136
FT                   /note="Gnk2-homologous 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
FT   DOMAIN          151..259
FT                   /note="Gnk2-homologous 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00806"
SQ   SEQUENCE   284 AA;  31540 MW;  C0A450FBBF312F2B CRC64;
     MATFIRFTAP LFCFFFLFSL FSHQTMSQPQ HMATFCDDRL SDNFTQTSSY KANRETLLSS
     LRDRSSLGTY SNATIGLSPD TVYGMFLCRG DLTKTSCSDC VKTATLEITK NNNCTSRKTA
     LIFYEECMVR YSNVSFFTLV ELDGPYVAKY SLATFPTSLF SSFQQTLSNK VEQLIILIAS
     KSSLSASTPY YVKDISRVNE LEGSYTLDTV VQCSPDLDPA NCGVCLRLVV KGLSGCCTNA
     RFAQFYLSKC FLKYDTTGLP TSQSPSGSSS INVMKGEHNI CPRL