CRSP2_CAPHI
ID CRSP2_CAPHI Reviewed; 125 AA.
AC B3IWF8;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-NOV-2008, sequence version 2.
DT 25-MAY-2022, entry version 39.
DE RecName: Full=Calcitonin receptor-stimulating peptide 2;
DE Short=CRSP-2;
DE Flags: Precursor;
GN Name=CRSP2;
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Charles C.J., Katafuchi T., Yandle T.G., Minamino N.;
RT "Identification and biological activity of ovine and caprine calcitonin
RT receptor-Sti.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the calcitonin family. {ECO:0000305}.
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DR EMBL; AB364647; BAG50396.1; ALT_SEQ; mRNA.
DR RefSeq; NP_001272616.1; NM_001285687.1.
DR AlphaFoldDB; B3IWF8; -.
DR STRING; 9925.ENSCHIP00000033258; -.
DR GeneID; 100860822; -.
DR KEGG; chx:100860822; -.
DR CTD; 403414; -.
DR OrthoDB; 1547206at2759; -.
DR Proteomes; UP000291000; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR InterPro; IPR021117; Calcitonin-like.
DR InterPro; IPR021116; Calcitonin/adrenomedullin.
DR InterPro; IPR015476; Calcitonin_gene-rel_peptide.
DR InterPro; IPR001693; Calcitonin_peptide-like.
DR PANTHER; PTHR10505; PTHR10505; 1.
DR Pfam; PF00214; Calc_CGRP_IAPP; 1.
DR PRINTS; PR00817; CALCITONINB.
DR SMART; SM00113; CALCITONIN; 1.
PE 2: Evidence at transcript level;
KW Cleavage on pair of basic residues; Disulfide bond; Receptor;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT PROPEP 26..77
FT /evidence="ECO:0000250"
FT /id="PRO_0000353083"
FT PEPTIDE 80..125
FT /note="Calcitonin receptor-stimulating peptide 2"
FT /id="PRO_0000353084"
FT DISULFID 81..86
FT /evidence="ECO:0000250"
SQ SEQUENCE 125 AA; 14162 MW; 0DEAB00B245CF660 CRC64;
MGFWKFLPFL VLSFLVVYQA GMFQAAPFRS ALENDFDPAI LTEKEMCLLL AAVMNDYVQM
KTSELKQEAE HFHITAQKRS CNRATCVTHK MAGSLSRSGS EIKRNFMSTN VGSKAFGQRS
RDLQK