ID   CRTL_DICDI              Reviewed;         299 AA.
AC   Q869N6; Q55AG4;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=3-hydroxybutyryl-CoA dehydratase-like protein, mitochondrial;
DE            EC=4.2.1.-;
DE   Flags: Precursor;
GN   ORFNames=DDB_G0271866;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000007; EAL71512.1; -; Genomic_DNA.
DR   RefSeq; XP_645447.1; XM_640355.1.
DR   AlphaFoldDB; Q869N6; -.
DR   SMR; Q869N6; -.
DR   STRING; 44689.DDB0168543; -.
DR   PaxDb; Q869N6; -.
DR   EnsemblProtists; EAL71512; EAL71512; DDB_G0271866.
DR   GeneID; 8618187; -.
DR   KEGG; ddi:DDB_G0271866; -.
DR   dictyBase; DDB_G0271866; -.
DR   eggNOG; KOG1680; Eukaryota.
DR   HOGENOM; CLU_009834_7_2_1; -.
DR   InParanoid; Q869N6; -.
DR   OMA; SCDMVVC; -.
DR   PhylomeDB; Q869N6; -.
DR   PRO; PR:Q869N6; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; IBA:GO_Central.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IBA:GO_Central.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE   3: Inferred from homology;
KW   Lyase; Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..14
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           15..299
FT                   /note="3-hydroxybutyryl-CoA dehydratase-like protein,
FT                   mitochondrial"
FT                   /id="PRO_0000331382"
SQ   SEQUENCE   299 AA;  32913 MW;  A2088A7885198613 CRC64;
     MINRLFSINN IKNGSKFFSS STTVETKQPL VLLEKHLVNG KYTGIQIVKL NKPKQLNALT
     FEMGVDYKKV VDTLAEDKDL KCVVLTGEGK AFSAGGDLDF LIERTKDTPE NNQRIMERFY
     RTFLYIRSLP VPIISAINGA AIGAGFCLAL ATDIRVVSNK APVGLTFTKL GIHPGMGVTH
     SITNIVGQDV ASYMLLSSDI IKGDEAQRLG LVLKSVESDQ VLPTALNLAE TISKNSTIAV
     NSTTKTLRNK YNSDLDKSLT READAQSQCW ASKDIVEGIL AIRESRDPKH NYLLFDDQK