CRTP1_MOUSE
ID CRTP1_MOUSE Reviewed; 142 AA.
AC Q9D1E4; Q9D7M7;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Cysteine-rich tail protein 1;
GN Name=Cysrt1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the CYSRT1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK003658; BAB22920.1; -; mRNA.
DR EMBL; AK009095; BAB26066.1; -; mRNA.
DR EMBL; AL732309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC117777; AAI17778.1; -; mRNA.
DR EMBL; BC117778; AAI17779.1; -; mRNA.
DR CCDS; CCDS50526.1; -.
DR RefSeq; NP_080691.2; NM_026415.3.
DR AlphaFoldDB; Q9D1E4; -.
DR BioGRID; 212486; 1.
DR STRING; 10090.ENSMUSP00000140416; -.
DR iPTMnet; Q9D1E4; -.
DR PhosphoSitePlus; Q9D1E4; -.
DR PaxDb; Q9D1E4; -.
DR PRIDE; Q9D1E4; -.
DR ProteomicsDB; 285368; -.
DR Antibodypedia; 8700; 55 antibodies from 9 providers.
DR DNASU; 67859; -.
DR Ensembl; ENSMUST00000043379; ENSMUSP00000045363; ENSMUSG00000036731.
DR Ensembl; ENSMUST00000186719; ENSMUSP00000140416; ENSMUSG00000036731.
DR GeneID; 67859; -.
DR KEGG; mmu:67859; -.
DR UCSC; uc008iqv.2; mouse.
DR CTD; 375791; -.
DR MGI; MGI:1915109; Cysrt1.
DR VEuPathDB; HostDB:ENSMUSG00000036731; -.
DR eggNOG; ENOG502SD8F; Eukaryota.
DR GeneTree; ENSGT00390000003233; -.
DR HOGENOM; CLU_126077_0_0_1; -.
DR InParanoid; Q9D1E4; -.
DR OMA; CHSCCCV; -.
DR OrthoDB; 1474726at2759; -.
DR PhylomeDB; Q9D1E4; -.
DR TreeFam; TF338434; -.
DR BioGRID-ORCS; 67859; 1 hit in 74 CRISPR screens.
DR PRO; PR:Q9D1E4; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q9D1E4; protein.
DR Bgee; ENSMUSG00000036731; Expressed in esophagus and 70 other tissues.
DR ExpressionAtlas; Q9D1E4; baseline and differential.
DR Genevisible; Q9D1E4; MM.
DR GO; GO:0042802; F:identical protein binding; ISO:MGI.
DR InterPro; IPR018904; UPF0574.
DR PANTHER; PTHR37879; PTHR37879; 1.
DR Pfam; PF10631; DUF2477; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..142
FT /note="Cysteine-rich tail protein 1"
FT /id="PRO_0000332288"
FT REGION 28..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 53
FT /note="E -> K (in Ref. 1; BAB26066)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 142 AA; 15108 MW; 87BAAB73A7595FB6 CRC64;
MDPHEMVVKN PYAHISIPRA HLRSDLGQQL EEVPSSSSSS ETQPLPAGTC IPEPVGLLQT
TEAPGPKGIK GIKGTAPEHG QQTWQSPCNP YSSGQRPSGL TYAGLPPVGR GDDIAHHCCC
CPCCSCCHCP RFCRCHSCCV IS
