ID   CRU1_SINAL              Reviewed;          56 AA.
AC   P83908;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Cruciferin;
DE   AltName: Full=11S globulin;
DE   AltName: Full=12S storage protein;
DE   AltName: Allergen=Sin a 2;
DE   Contains:
DE     RecName: Full=Cruciferin alpha chain;
DE   Contains:
DE     RecName: Full=Cruciferin beta chain;
DE   Flags: Fragments;
OS   Sinapis alba (White mustard) (Brassica hirta).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Sinapis.
OX   NCBI_TaxID=3728;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND ALLERGEN.
RC   TISSUE=Seed {ECO:0000269|PubMed:15945563};
RX   PubMed=15945563; DOI=10.1016/s1081-1206(10)61138-6;
RA   Palomares O., Cuesta-Herranz J., Vereda A., Sirvent S., Villalba M.,
RA   Rodriguez R.;
RT   "Isolation and identification of an 11S globulin as a new major allergen in
RT   mustard seeds.";
RL   Ann. Allergy Asthma Immunol. 94:586-592(2005).
CC   -!- FUNCTION: This is a seed storage protein. {ECO:0000305}.
CC   -!- SUBUNIT: Hexamer; each subunit is composed of an acidic and a basic
CC       chain derived from a single precursor and linked by a disulfide bond.
CC       {ECO:0000305}.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC       {ECO:0000269|PubMed:15945563}.
CC   -!- SIMILARITY: Belongs to the 11S seed storage protein (globulins) family.
CC       {ECO:0000255}.
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DR   AlphaFoldDB; P83908; -.
DR   SMR; P83908; -.
DR   Allergome; 2693; Sin a 2.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Disulfide bond; Phosphoprotein;
KW   Seed storage protein; Storage protein.
FT   CHAIN           1..>22
FT                   /note="Cruciferin alpha chain"
FT                   /evidence="ECO:0000250|UniProtKB:Q02498"
FT                   /id="PRO_0000032042"
FT   CHAIN           <23..>56
FT                   /note="Cruciferin beta chain"
FT                   /evidence="ECO:0000250|UniProtKB:Q02498"
FT                   /id="PRO_0000032043"
FT   MOD_RES         45
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P15456"
FT   NON_CONS        9..10
FT                   /evidence="ECO:0000303|PubMed:15945563"
FT   NON_CONS        22..23
FT                   /evidence="ECO:0000303|PubMed:15945563"
FT   NON_CONS        37..38
FT                   /evidence="ECO:0000303|PubMed:15945563"
FT   NON_TER         56
FT                   /evidence="ECO:0000303|PubMed:15945563"
SQ   SEQUENCE   56 AA;  6302 MW;  6DECC3DF82AC2737 CRC64;
     RQSLGVPPQV KGPFQVVRPP LRTSVNSYTL PILQYIRALP LEVITNAFQI SLEEAR