CRVPA_NOTSC
ID CRVPA_NOTSC Reviewed; 22 AA.
AC P0DL19;
DT 01-MAY-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2013, sequence version 1.
DT 25-MAY-2022, entry version 14.
DE RecName: Full=Cysteine-rich venom protein notescatin;
DE Short=CRVP;
DE AltName: Full=Notescatin-a;
DE AltName: Full=Notescatin-b;
DE Flags: Fragment;
OS Notechis scutatus scutatus (Mainland tiger snake) (Common tiger snake).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Acanthophiinae; Notechis.
OX NCBI_TaxID=70142;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Venom;
RX PubMed=19106157; DOI=10.1093/jb/mvn174;
RA Matsunaga Y., Yamazaki Y., Hyodo F., Sugiyama Y., Nozaki M., Morita T.;
RT "Structural divergence of cysteine-rich secretory proteins in snake
RT venoms.";
RL J. Biochem. 145:365-375(2009).
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC -!- PTM: Contains 8 disulfide bonds. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
CC -!- CAUTION: Two CRISP proteins (notescatin-a and -b) are secreted in the
CC venom of N.scutatus. Since the N-terminal amino-acid sequence of these
CC two proteins is identical, only one UniProtKB entry has been created
CC (PubMed:19106157). {ECO:0000305|PubMed:19106157}.
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DR AlphaFoldDB; P0DL19; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT CHAIN 1..>22
FT /note="Cysteine-rich venom protein notescatin"
FT /id="PRO_0000422149"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 22
SQ SEQUENCE 22 AA; 2657 MW; 1A781D62C6DAC2A7 CRC64;
SNKKDYQKEI VDKHNALRRS VK