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CRVPA_NOTSC
ID   CRVPA_NOTSC             Reviewed;          22 AA.
AC   P0DL19;
DT   01-MAY-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2013, sequence version 1.
DT   25-MAY-2022, entry version 14.
DE   RecName: Full=Cysteine-rich venom protein notescatin;
DE            Short=CRVP;
DE   AltName: Full=Notescatin-a;
DE   AltName: Full=Notescatin-b;
DE   Flags: Fragment;
OS   Notechis scutatus scutatus (Mainland tiger snake) (Common tiger snake).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Acanthophiinae; Notechis.
OX   NCBI_TaxID=70142;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Venom;
RX   PubMed=19106157; DOI=10.1093/jb/mvn174;
RA   Matsunaga Y., Yamazaki Y., Hyodo F., Sugiyama Y., Nozaki M., Morita T.;
RT   "Structural divergence of cysteine-rich secretory proteins in snake
RT   venoms.";
RL   J. Biochem. 145:365-375(2009).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- PTM: Contains 8 disulfide bonds. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
CC   -!- CAUTION: Two CRISP proteins (notescatin-a and -b) are secreted in the
CC       venom of N.scutatus. Since the N-terminal amino-acid sequence of these
CC       two proteins is identical, only one UniProtKB entry has been created
CC       (PubMed:19106157). {ECO:0000305|PubMed:19106157}.
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DR   AlphaFoldDB; P0DL19; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT   CHAIN           1..>22
FT                   /note="Cysteine-rich venom protein notescatin"
FT                   /id="PRO_0000422149"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         22
SQ   SEQUENCE   22 AA;  2657 MW;  1A781D62C6DAC2A7 CRC64;
     SNKKDYQKEI VDKHNALRRS VK
 
 
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