CRVPO_NAJKA
ID CRVPO_NAJKA Reviewed; 23 AA.
AC P84803;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 02-JUN-2021, entry version 23.
DE RecName: Full=Cysteine-rich venom protein 24;
DE AltName: Full=CRVP-24k;
DE Flags: Fragment;
OS Naja kaouthia (Monocled cobra) (Naja siamensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Naja.
OX NCBI_TaxID=8649;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND MASS
RP SPECTROMETRY.
RC TISSUE=Venom {ECO:0000269|PubMed:15670767};
RX PubMed=15670767; DOI=10.1016/j.bbrc.2004.12.154;
RA Osipov A.V., Levashov M.Y., Tsetlin V.I., Utkin Y.N.;
RT "Cobra venom contains a pool of cysteine-rich secretory proteins.";
RL Biochem. Biophys. Res. Commun. 328:177-182(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15670767}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000269|PubMed:15670767}.
CC -!- PTM: Contains 8 disulfide bonds. {ECO:0000250|UniProtKB:P84808}.
CC -!- MASS SPECTROMETRY: Mass=24080; Method=MALDI; Note=It is not clear why
CC there are two peaks for this protein.;
CC Evidence={ECO:0000269|PubMed:15670767};
CC -!- MASS SPECTROMETRY: Mass=24704; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:15670767};
CC -!- MISCELLANEOUS: Not toxic when administered to cockroaches at doses up
CC to 5 nmol/g. {ECO:0000269|PubMed:15670767}.
CC -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000255}.
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DR GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IDA:UniProtKB.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT CHAIN 1..>23
FT /note="Cysteine-rich venom protein 24"
FT /id="PRO_0000231639"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 23
FT /evidence="ECO:0000303|PubMed:15670767"
SQ SEQUENCE 23 AA; 2654 MW; 71CA4E2350FEB709 CRC64;
VDFASESXNK RENQQIVDKH NAL