ID   CRVP_TRILK              Reviewed;         406 AA.
AC   W4VS53;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   19-MAR-2014, sequence version 1.
DT   25-MAY-2022, entry version 15.
DE   RecName: Full=CRISP/Allergen/PR-1;
DE            Short=Cap-1;
DE   Flags: Precursor;
OS   Trittame loki (Brush-footed trapdoor spider).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Mygalomorphae; Barychelidae; Trittame.
OX   NCBI_TaxID=1295018;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION BY MASS SPECTROMETRY, AND
RP   SUBCELLULAR LOCATION.
RC   TISSUE=Venom, and Venom gland;
RX   PubMed=24351713; DOI=10.3390/toxins5122488;
RA   Undheim E.A., Sunagar K., Herzig V., Kely L., Low D.H., Jackson T.N.,
RA   Jones A., Kurniawan N., King G.F., Ali S.A., Antunes A., Ruder T.,
RA   Fry B.G.;
RT   "A proteomics and transcriptomics investigation of the venom from the
RT   barychelid spider Trittame loki (brush-foot trapdoor).";
RL   Toxins 5:2488-2503(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:24351713}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:24351713}.
CC   -!- PTM: Contains 9 disulfide bonds. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
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DR   EMBL; GAQE01000003; JAB84551.1; -; Transcribed_RNA.
DR   AlphaFoldDB; W4VS53; -.
DR   SMR; W4VS53; -.
DR   ArachnoServer; AS001967; CRISP-1-Trittame loki.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.33.10; -; 1.
DR   InterPro; IPR018244; Allrgn_V5/Tpx1_CS.
DR   InterPro; IPR014044; CAP_domain.
DR   InterPro; IPR035940; CAP_sf.
DR   InterPro; IPR001283; CRISP-related.
DR   InterPro; IPR002413; V5_allergen-like.
DR   PANTHER; PTHR10334; PTHR10334; 1.
DR   Pfam; PF00188; CAP; 1.
DR   PRINTS; PR00838; V5ALLERGEN.
DR   PRINTS; PR00837; V5TPXLIKE.
DR   SMART; SM00198; SCP; 1.
DR   SUPFAM; SSF55797; SSF55797; 1.
DR   PROSITE; PS01010; CRISP_2; 1.
PE   1: Evidence at protein level;
KW   Disulfide bond; Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..406
FT                   /note="CRISP/Allergen/PR-1"
FT                   /evidence="ECO:0000305|PubMed:24351713"
FT                   /id="PRO_0000429206"
FT   DOMAIN          58..205
FT                   /note="SCP"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        39
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   406 AA;  44514 MW;  3F17BF410D920523 CRC64;
     MHFQVILMMM WLWLEAEGGT CPTLYKRYSK HHTYCLHPNS TCKILTRGVS SGDKEIILRE
     HNKLRSRVAT GKETKYSLPK ASDMMQLVWD DELASVAQKH ADQCVFEHDC NDCRNVQNFG
     VGQNLHLRTS SAKFSDITWA GAVNGWYDEV KDFNKRQISG FIDGKGPPQT GHFTQAVWAT
     SWRVGCGRSM FKDGNTFKDL YTCNYGPGGN MKNAIIYTKG KPCSGCPLNS CCGKACGGIS
     YDGLCKMSGN TAPQYSPPKG FAFRCTFNGE SDCATTTSGA KKWKTIKTLS GSFIGIVLNP
     GESSTLSFTV PFGVSDGSMC VESYYRKGPQ VAGQVAAGNA VEKFGDPADP SFDYSTPLKE
     STDFMQFGVT LGWNTKTTLS VVFSVPPGTA PQYLEMKDIS VRKGEC