ID   CRYD_OSTTA              Reviewed;         546 AA.
AC   Q5IFN2; A0A090N2W1; Q01FE7;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Cryptochrome DASH, chloroplastic/mitochondrial;
DE   Flags: Precursor;
GN   OrderedLocusNames=Ot01g06470 {ECO:0000312|EMBL:CEF96928.1};
OS   Ostreococcus tauri.
OC   Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC   Bathycoccaceae; Ostreococcus.
OX   NCBI_TaxID=70448;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Bouget F.-Y., Schwartz C., Camasses A., Corellou F.,
RA   de Oliveira Manes C.M., Moulanger M., Ferraz C., Demaille J., Moreau H.,
RA   Derelle E., Delseny M., Cooke R., Rombault S.;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OTTH0595;
RX   PubMed=16868079; DOI=10.1073/pnas.0604795103;
RA   Derelle E., Ferraz C., Rombauts S., Rouze P., Worden A.Z., Robbens S.,
RA   Partensky F., Degroeve S., Echeynie S., Cooke R., Saeys Y., Wuyts J.,
RA   Jabbari K., Bowler C., Panaud O., Piegu B., Ball S.G., Ral J.-P.,
RA   Bouget F.-Y., Piganeau G., De Baets B., Picard A., Delseny M., Demaille J.,
RA   Van de Peer Y., Moreau H.;
RT   "Genome analysis of the smallest free-living eukaryote Ostreococcus tauri
RT   unveils many unique features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:11647-11652(2006).
CC   -!- FUNCTION: May have a photoreceptor function. Binds ss- and ds-DNA in a
CC       sequence non-specific manner, lacks photolyase activity (By
CC       similarity). {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
CC       Note=Binds 1 FAD per subunit. {ECO:0000250};
CC   -!- COFACTOR:
CC       Name=(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate;
CC         Xref=ChEBI:CHEBI:15636; Evidence={ECO:0000250};
CC       Note=Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
CC       {ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}. Mitochondrion
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DNA photolyase class-1 family.
CC       {ECO:0000305}.
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DR   EMBL; AY740084; AAU14279.1; -; Genomic_DNA.
DR   EMBL; CAID01000001; CEF96928.1; -; Genomic_DNA.
DR   RefSeq; XP_003074697.1; XM_003074649.1.
DR   AlphaFoldDB; Q5IFN2; -.
DR   SMR; Q5IFN2; -.
DR   STRING; 70448.A0A090N2W1; -.
DR   GeneID; 9836488; -.
DR   KEGG; ota:OT_ostta01g06470; -.
DR   eggNOG; KOG0133; Eukaryota.
DR   InParanoid; Q5IFN2; -.
DR   OrthoDB; 378952at2759; -.
DR   Proteomes; UP000009170; Chromosome 1.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003904; F:deoxyribodipyrimidine photo-lyase activity; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0071949; F:FAD binding; IBA:GO_Central.
DR   GO; GO:0000719; P:photoreactive repair; IBA:GO_Central.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014133; Cry_DASH.
DR   InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR   InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR   InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR   InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR   InterPro; IPR018394; DNA_photolyase_1_CS_C.
DR   InterPro; IPR006050; DNA_photolyase_N.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR11455; PTHR11455; 1.
DR   Pfam; PF00875; DNA_photolyase; 1.
DR   Pfam; PF03441; FAD_binding_7; 1.
DR   PRINTS; PR00147; DNAPHOTLYASE.
DR   SUPFAM; SSF48173; SSF48173; 1.
DR   SUPFAM; SSF52425; SSF52425; 1.
DR   TIGRFAMs; TIGR02765; crypto_DASH; 1.
DR   PROSITE; PS00394; DNA_PHOTOLYASES_1_1; 1.
DR   PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Chromophore; DNA-binding; FAD; Flavoprotein; Mitochondrion;
KW   Plastid; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Chloroplast and mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..546
FT                   /note="Cryptochrome DASH, chloroplastic/mitochondrial"
FT                   /id="PRO_0000235321"
FT   DOMAIN          4..151
FT                   /note="Photolyase/cryptochrome alpha/beta"
FT   REGION          497..546
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   546 AA;  60980 MW;  F71C28BA858BCF57 CRC64;
     MGRTRVVIWF RNDLRLLDNA CVARAATLAS ESSDVEVVPV YVFDETYFKP SKRGLARFGA
     GRGKFTLECV GDLKTSLRAL GSDLLVRCGK SRDVIAELTL TGANDRTIIL TQTEVTSEET
     EMDVAVERAT RERARGGAAS ATMERHWGST LYHIDDVPFD VTSGLSDLPD VFTPFRNKVE
     SKCKVRDVIP APTANELGHV PASVEGFEWM PKPSDLPFAS SEIAMDCDKR IKDCLDERSV
     LDFKGGESNA LARVKYYLWE SDRLATYFET RNGMLGGDYS TKLAPWLALG CVSPRHVVSE
     IRRYESERVE NKSTYWVIFE LIWRDFFKFF ALKHGNKIFH LDGTAGRRAS WKRDEKILKA
     WKTGTTGYPL IDANMRELAA TGFMSNRGRQ NVASWLALDA GIDWRHGADW FEHHLLDYDT
     ASNWGNWCAA AGMTGGRINR FNIAKQTKDY DPAGEYIKTW VKELAEVPAA YIADPNQAPR
     ELRDRIGLNY PNKLALPRRD FTEMGSPPGP RRGGGGGGRG RGRPGGSTPN RGTKARVASV
     YDTVYG