ID   CS012_XENTR             Reviewed;         141 AA.
AC   Q6DJ35;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Protein C19orf12 homolog;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9NSK7}.
CC       Mitochondrion membrane {ECO:0000250|UniProtKB:Q9NSK7}; Single-pass
CC       membrane protein {ECO:0000255}. Endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q9NSK7}. Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:Q9NSK7}. Note=In response to oxidative stress,
CC       relocates to the cytosol forming aggregates that partially co-localize
CC       with mitochondria. {ECO:0000250|UniProtKB:Q9NSK7}.
CC   -!- SIMILARITY: Belongs to the C19orf12 family. {ECO:0000305}.
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DR   EMBL; BC075349; AAH75349.1; -; mRNA.
DR   RefSeq; NP_001004911.1; NM_001004911.1.
DR   RefSeq; XP_012816288.1; XM_012960834.2.
DR   RefSeq; XP_012816289.1; XM_012960835.2.
DR   RefSeq; XP_012816290.1; XM_012960836.2.
DR   AlphaFoldDB; Q6DJ35; -.
DR   PaxDb; Q6DJ35; -.
DR   DNASU; 448278; -.
DR   Ensembl; ENSXETT00000022991; ENSXETP00000022991; ENSXETG00000010474.
DR   GeneID; 448278; -.
DR   KEGG; xtr:448278; -.
DR   CTD; 83636; -.
DR   Xenbase; XB-GENE-1009748; c19orf12.
DR   eggNOG; ENOG502RZQC; Eukaryota.
DR   HOGENOM; CLU_138025_0_0_1; -.
DR   InParanoid; Q6DJ35; -.
DR   OMA; LCCEIST; -.
DR   OrthoDB; 1474873at2759; -.
DR   PhylomeDB; Q6DJ35; -.
DR   TreeFam; TF323308; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000010474; Expressed in liver and 13 other tissues.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   InterPro; IPR033369; C19orf12.
DR   PANTHER; PTHR31493; PTHR31493; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Endoplasmic reticulum; Membrane; Mitochondrion;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..141
FT                   /note="Protein C19orf12 homolog"
FT                   /id="PRO_0000296665"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   141 AA;  15073 MW;  E1945C9B0BDE55F5 CRC64;
     MPVQVDDIIK LLCHVSDHQK MKATIKHSAR GALVAAAGAF LGGLVGGPPG IAVGGAVGGA
     MGAWMTSGQF KPIPQIIMEL PPVQQQRLCD DIYTIVRTLD WTDATQLIML VMGNDSLKQK
     VVAALINYMT KELQAEIQYG D