CS044_MOUSE
ID CS044_MOUSE Reviewed; 641 AA.
AC Q922C1; Q3UZJ9;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 26-JUN-2007, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Uncharacterized protein C19orf44 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006;
RA Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,
RA Thibault P.;
RT "The phagosomal proteome in interferon-gamma-activated macrophages.";
RL Immunity 30:143-154(2009).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK133815; BAE21858.1; -; mRNA.
DR EMBL; BC008558; AAH08558.1; -; mRNA.
DR CCDS; CCDS22414.1; -.
DR RefSeq; NP_082446.2; NM_028170.2.
DR AlphaFoldDB; Q922C1; -.
DR SMR; Q922C1; -.
DR STRING; 10090.ENSMUSP00000063244; -.
DR iPTMnet; Q922C1; -.
DR PhosphoSitePlus; Q922C1; -.
DR PaxDb; Q922C1; -.
DR PRIDE; Q922C1; -.
DR Antibodypedia; 51085; 65 antibodies from 16 providers.
DR Ensembl; ENSMUST00000064853; ENSMUSP00000063244; ENSMUSG00000052794.
DR GeneID; 72254; -.
DR KEGG; mmu:72254; -.
DR UCSC; uc009mfy.2; mouse.
DR MGI; MGI:1919504; 1700030K09Rik.
DR VEuPathDB; HostDB:ENSMUSG00000052794; -.
DR eggNOG; ENOG502RMHR; Eukaryota.
DR GeneTree; ENSGT00390000002505; -.
DR InParanoid; Q922C1; -.
DR OMA; AREYIRC; -.
DR OrthoDB; 878530at2759; -.
DR PhylomeDB; Q922C1; -.
DR TreeFam; TF330762; -.
DR BioGRID-ORCS; 72254; 2 hits in 73 CRISPR screens.
DR PRO; PR:Q922C1; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q922C1; protein.
DR Bgee; ENSMUSG00000052794; Expressed in seminiferous tubule of testis and 242 other tissues.
DR ExpressionAtlas; Q922C1; baseline and differential.
DR Genevisible; Q922C1; MM.
DR InterPro; IPR040120; C19orf44-like.
DR InterPro; IPR027884; DUF4614.
DR PANTHER; PTHR22409; PTHR22409; 1.
DR Pfam; PF15391; DUF4614; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..641
FT /note="Uncharacterized protein C19orf44 homolog"
FT /id="PRO_0000291922"
FT REGION 118..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..370
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 112
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9H6X5"
FT MOD_RES 198
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6AXP1"
FT CONFLICT 73
FT /note="S -> I (in Ref. 2; AAH08558)"
FT /evidence="ECO:0000305"
FT CONFLICT 208
FT /note="R -> G (in Ref. 2; AAH08558)"
FT /evidence="ECO:0000305"
FT CONFLICT 289
FT /note="I -> M (in Ref. 2; AAH08558)"
FT /evidence="ECO:0000305"
FT CONFLICT 392
FT /note="N -> T (in Ref. 2; AAH08558)"
FT /evidence="ECO:0000305"
FT CONFLICT 398
FT /note="T -> A (in Ref. 2; AAH08558)"
FT /evidence="ECO:0000305"
FT CONFLICT 405
FT /note="G -> E (in Ref. 2; AAH08558)"
FT /evidence="ECO:0000305"
FT CONFLICT 407
FT /note="G -> D (in Ref. 2; AAH08558)"
FT /evidence="ECO:0000305"
FT CONFLICT 576
FT /note="H -> Q (in Ref. 2; AAH08558)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 641 AA; 69273 MW; 44A54D0521CE0FB8 CRC64;
MASTRRPFGP PRSGFDLRDM FLDSSRMEEI RNLQARSLGQ VTPGQSRILK RNQTMDEKYL
MPKEEAMAGR GVSLGLRPPT ISSKTRASEA LRKLAQIETK ILNRKQVPMA WSDVESDSTS
IEQSLPKRTG AASVSSQYPH RTFQKQVNKT CVSKSDGPSG NGSRFLKKKE LPTEARSPGL
AVGTGKQALL PTKKESASDE EEEMLLLRSL MESSREKEAN RNQELPGSSV SRSNLGKVFL
DPTPDQPGVL SLLSVDQSSL KSPRPIQSTR VGLRTHSRQA SSAGDTVSIT ASPPILDDFS
KSASSKMGCI KLASSPSRTE LESSEEPVSE AAADSLHDFR INILSIDDLV LADGDKSDGD
QREEDCVREG ISVRSSSPTS PTRLEAQMWP KNCVFQGTAT VVGDGEGLTT ESDVSEPPGT
SSSAAVQSHS MSRALTASPA YSEDFEQFSG PLALEESLDR TLDTLSKFSS SGQTDIVARQ
PLSRTEWGRG VTRVVKETAV QTLDPAFAYQ WSKAGGIAAV GPALGGAYVD PAPIASHIVS
ADAIEALTAY SPAVLALNDM LKQQLSLTQQ FIEASHQLHG SLLQSLDGDS FHYHTLEEAK
EYIRCHRPAP LTMEAALQEV REELQVPASE ACLGTCPPRN Q
