CS067_MOUSE
ID CS067_MOUSE Reviewed; 301 AA.
AC Q8CF25; F6UZF9;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2012, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=UPF0575 protein C19orf67 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
CC -!- SIMILARITY: Belongs to the UPF0575 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC25156.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AK006917; BAC25156.1; ALT_FRAME; mRNA.
DR EMBL; AC156028; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_898920.2; NM_183097.2.
DR AlphaFoldDB; Q8CF25; -.
DR SMR; Q8CF25; -.
DR STRING; 10090.ENSMUSP00000062468; -.
DR PhosphoSitePlus; Q8CF25; -.
DR PaxDb; Q8CF25; -.
DR PRIDE; Q8CF25; -.
DR GeneID; 73453; -.
DR KEGG; mmu:73453; -.
DR UCSC; uc012ggv.1; mouse.
DR MGI; MGI:1920703; 1700067K01Rik.
DR VEuPathDB; HostDB:ENSMUSG00000046408; -.
DR eggNOG; ENOG502R1CJ; Eukaryota.
DR HOGENOM; CLU_069377_0_0_1; -.
DR InParanoid; Q8CF25; -.
DR OrthoDB; 855013at2759; -.
DR TreeFam; TF337776; -.
DR BioGRID-ORCS; 73453; 2 hits in 71 CRISPR screens.
DR PRO; PR:Q8CF25; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; Q8CF25; protein.
DR Genevisible; Q8CF25; MM.
DR GO; GO:0001701; P:in utero embryonic development; IMP:MGI.
DR InterPro; IPR021748; DUF3314.
DR PANTHER; PTHR36292; PTHR36292; 1.
DR Pfam; PF11771; DUF3314; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..301
FT /note="UPF0575 protein C19orf67 homolog"
FT /id="PRO_0000332938"
FT CONFLICT 13
FT /note="P -> Q (in Ref. 1; BAC25156)"
FT /evidence="ECO:0000305"
FT CONFLICT 41
FT /note="L -> V (in Ref. 1; BAC25156)"
FT /evidence="ECO:0000305"
FT CONFLICT 58
FT /note="R -> P (in Ref. 1; BAC25156)"
FT /evidence="ECO:0000305"
FT CONFLICT 75
FT /note="C -> W (in Ref. 1; BAC25156)"
FT /evidence="ECO:0000305"
FT CONFLICT 90..91
FT /note="PP -> LS (in Ref. 1; BAC25156)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 301 AA; 33638 MW; 9800252CA425A9BF CRC64;
MMEAPASTSS REPLAAELGP APARLPLDSM FSPITDQLRY LLRKADDFQS YLLYSRDRVQ
KEQLAKAMPT FLTMCEPYFL YLEAAARSVP PIYGALQELV RKGLLEISQQ LTLRLEQLVL
MYASFGFVDL EETNPLSISC FFCGRFSISP SHDVSIFRYC TPAAYTASHF PRYLYKKMRW
NLETTTEASS QGADSHVDYY FLCYRDTWED AGQGPANSCP QIQKLWSIGR WMPLGPAEDD
LDSWILCPQP PGDYQQLLTI GFEEPSHVLA TDLLVQILLG QAGPARPPSA AGPAAWAAPA
S