ID   CS111_CANGA             Reviewed;         932 AA.
AC   Q6FJL1;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=F-box protein COS111;
GN   Name=COS111; OrderedLocusNames=CAGL0M05445g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: F-box protein probably involved in ubiquitin conjugation
CC       pathway. {ECO:0000250}.
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DR   EMBL; CR380959; CAG62559.1; -; Genomic_DNA.
DR   RefSeq; XP_449583.1; XM_449583.1.
DR   AlphaFoldDB; Q6FJL1; -.
DR   STRING; 5478.XP_449583.1; -.
DR   PRIDE; Q6FJL1; -.
DR   EnsemblFungi; CAG62559; CAG62559; CAGL0M05445g.
DR   GeneID; 2891630; -.
DR   KEGG; cgr:CAGL0M05445g; -.
DR   CGD; CAL0136983; CAGL0M05445g.
DR   VEuPathDB; FungiDB:CAGL0M05445g; -.
DR   eggNOG; ENOG502R67H; Eukaryota.
DR   HOGENOM; CLU_017243_0_0_1; -.
DR   InParanoid; Q6FJL1; -.
DR   OMA; LLKYAPY; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0007165; P:signal transduction; IEA:EnsemblFungi.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   Pfam; PF12937; F-box-like; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..932
FT                   /note="F-box protein COS111"
FT                   /id="PRO_0000279193"
FT   DOMAIN          146..193
FT                   /note="F-box"
FT   REGION          29..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          346..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          389..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          470..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          863..893
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..63
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        876..890
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   932 AA;  105031 MW;  3288F72DBF81253E CRC64;
     MQSVNIVSTN YSRYGVSVYD RLYRKDKNVS AKHRPSSTGV YGHDASTVDH ASRSNNNLNL
     TRSTSAISES DDVATISTNN SRRSVIKRKY KSLITASSKK LITKLYEHGS NSDSFSIFSH
     KTSQSHHPAQ RLGTEEDLII NDLFKRKEIS DLPDEVLRNI LSNVKDDQRT LVNCLYVNKA
     FYNATKPTLY ERPKFTSTYR VAQFVTSIRT NPQNGLYVRE LDLSKLKNGS LNGKSTSNTG
     VVADSPDVDE YNPMRTRTGS VTSFTSVTST ANSNTALSIT TNNKDVALAG WRDWRYRHDP
     LYSSPVLNSY NAKRTVSRAP SIKSSHSSSS LTLFPGLKSK ESFAQLSEGK SSDNGNNGKR
     QRSNSSVSSI TNSLMSSLYN GSHISLNTTL SGSDNNSSKT QSKGKSSSSP GNPNDSSGEQ
     DSIISSSSQI DTNTFGMTSS KSTSSTSNWF RMKLHGNGTR KLRLRSNKAI SSKKDEQQNE
     ESAQTAQKIE TPIIKRTEPF STPHPYTNKF LLKYAQYKDL PLGYILHILD HCPYLYILDL
     SNLTLCTDFE IIEGRRYKGR KQRFGSSRAL PVVQESVIST DVPNDLDVIY LTDSSKTYEY
     YDRLRNTNKH KRSSSSNNLW SIPNQGWSDA PAPIGSHKND LRRTHSQTIG RSNVELRKLN
     ASEIFEHIAT NQKSAYNTHL RVYMKNVLWC TQDMVKSFVL ENFDQQAENL GEDKSSEMFI
     HDMNFSFENS GLNRNFVWTC EGNLQEFIAM VVLDEVNRKD DLEIENLFNI KAERILTPTN
     GPERAPEVHY ISNVFTVSYG FQSNKKREMK FRVTILKTDT PMYFSIKKLA DDYTSVVIKL
     QTNKNVALHG SETADIITTD QGSVLPEDVP EDNNADDTNN GENTIAQPFS NDPKERIERI
     TQEIVARLKD LRGSDLRRNI GENNYVRERF LL