ID   CS111_YARLI             Reviewed;         555 AA.
AC   Q6CG37;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=F-box protein COS111;
GN   Name=COS111; OrderedLocusNames=YALI0B01166g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: F-box protein probably involved in ubiquitin conjugation
CC       pathway. {ECO:0000250}.
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DR   EMBL; CR382128; CAG82590.1; -; Genomic_DNA.
DR   RefSeq; XP_500375.1; XM_500375.1.
DR   AlphaFoldDB; Q6CG37; -.
DR   STRING; 4952.CAG82590; -.
DR   EnsemblFungi; CAG82590; CAG82590; YALI0_B01166g.
DR   GeneID; 2907522; -.
DR   KEGG; yli:YALI0B01166g; -.
DR   VEuPathDB; FungiDB:YALI0_B01166g; -.
DR   HOGENOM; CLU_491091_0_0_1; -.
DR   InParanoid; Q6CG37; -.
DR   OMA; LASWRDW; -.
DR   Proteomes; UP000001300; Chromosome B.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   Pfam; PF12937; F-box-like; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..555
FT                   /note="F-box protein COS111"
FT                   /id="PRO_0000279196"
FT   DOMAIN          196..246
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REGION          31..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          124..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          327..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..345
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   555 AA;  62581 MW;  4DA96B5418D7F81F CRC64;
     MFTPQSISQR SNGLHFKRPV TYKTTMLHPV MSVSSRSSQE ESLMTVGESV SSLSMQEQQT
     ESDTDASHSD NEENDNVDSV SNFDNLSNSI HLISLNEVDE LLEDHQSTIQ SSLNRGLTCT
     NLPDHSIKSG VTRSTVSTVR PTSKQHHQPY KYRSLLLPFE PSRGSRSMRR KIGGSRGSSL
     ASVRRIFRST HHLQPHKDLN SLPHEIMSKI VSHLDQRDVT MCLYVNKNMY STAVRQLYKE
     PFFSSTYRFA QFVTQVSHND ELASYVQKLD LSTIRPGFES DEDDSAIFEN EPIEDDAVLA
     GWRDWKLRGD PLYSRQFKRL TKHVSNSSSS LSCSRTSSNS NSSTESKPVK KRRSVTTAIR
     ESRIWLSFYK KNKLYQASEE VLEALRKQNS PLVRPKVPFS TAHPISSPFL RQYSTSKDVP
     VGHLIHVVAA CKNLTDIDIS FLPLAEDYAV AGSSSYLPTA SSGLLFVSDV AKLYTWKPDE
     IVPVSPSDLV VAMLQLRDLQ VLKLRKLMWV KRDSVVRLVN ENNSLVHLDL TDSGLVRGAR
     WAIAGSVEEL RQTLK