CSA_ORYSJ
ID CSA_ORYSJ Reviewed; 338 AA.
AC Q5NBM8; Q0JNP4;
DT 30-AUG-2017, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2017, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Transcription factor CSA {ECO:0000305};
DE AltName: Full=Myb-related protein CSA {ECO:0000305};
DE AltName: Full=Protein CARBON STARVED ANTHER {ECO:0000303|PubMed:20305120};
GN Name=CSA {ECO:0000303|PubMed:20305120};
GN OrderedLocusNames=Os01g0274800 {ECO:0000312|EMBL:BAS71534.1},
GN LOC_Os01g16810 {ECO:0000305};
GN ORFNames=P0038F12.1 {ECO:0000312|EMBL:BAD81105.1},
GN P0424A08.17 {ECO:0000312|EMBL:BAD81128.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, INDUCTION BY WOUNDING, DEVELOPMENTAL STAGE,
RP AND DISRUPTION PHENOTYPE.
RX PubMed=20305120; DOI=10.1105/tpc.109.073668;
RA Zhang H., Liang W., Yang X., Luo X., Jiang N., Ma H., Zhang D.;
RT "Carbon starved anther encodes a MYB domain protein that regulates sugar
RT partitioning required for rice pollen development.";
RL Plant Cell 22:672-689(2010).
RN [6]
RP DISRUPTION PHENOTYPE.
RX PubMed=23256151; DOI=10.1073/pnas.1213041110;
RA Zhang H., Xu C., He Y., Zong J., Yang X., Si H., Sun Z., Hu J., Liang W.,
RA Zhang D.;
RT "Mutation in CSA creates a new photoperiod-sensitive genic male sterile
RT line applicable for hybrid rice seed production.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:76-81(2013).
CC -!- FUNCTION: Transcription factor required for sugar partitioning from
CC leaves to anthers during male reproductive development. Required for
CC the production of functional pollen grains. Binds to the promoter of
CC the anther-specific sugar transporter MST8 and regulates its
CC expression. Regulates the expression of genes involved in sugar
CC partitioning in flower, such as the sugar transporter SUT3, the
CC invertase INV4, the UDP-glucose pyrophosphorylase UGP2 and the starch
CC synthase WAXY. {ECO:0000269|PubMed:20305120}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20305120}.
CC -!- TISSUE SPECIFICITY: Expressed in root vascular tissue, primordia of
CC lateral roots, leaf collar, and veins of lemma, palea and pistil.
CC {ECO:0000269|PubMed:20305120}.
CC -!- DEVELOPMENTAL STAGE: During anther development, expressed in anther
CC vacuolar tissue from stage 9 to stage 13.
CC {ECO:0000269|PubMed:20305120}.
CC -!- INDUCTION: Induced by wounding. {ECO:0000269|PubMed:20305120}.
CC -!- DISRUPTION PHENOTYPE: Reduced plant size, and reduced levels of sugars
CC in anthers leading to defective anthers and male sterility when grown
CC under short day (12 hours light) conditions (PubMed:20305120,
CC PubMed:23256151). No male sterility phenotype when grown under long day
CC (14 hours light) conditions (PubMed:23256151).
CC {ECO:0000269|PubMed:20305120, ECO:0000269|PubMed:23256151}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD81105.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD81128.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF04634.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAS71534.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP000836; BAD81105.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP000837; BAD81128.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008207; BAF04634.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014957; BAS71534.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_015631112.1; XM_015775626.1.
DR AlphaFoldDB; Q5NBM8; -.
DR SMR; Q5NBM8; -.
DR STRING; 39947.Q5NBM8; -.
DR PaxDb; Q5NBM8; -.
DR PRIDE; Q5NBM8; -.
DR GeneID; 4325181; -.
DR KEGG; osa:4325181; -.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_18_1_1; -.
DR InParanoid; Q5NBM8; -.
DR OrthoDB; 1499244at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..338
FT /note="Transcription factor CSA"
FT /id="PRO_0000441043"
FT DOMAIN 44..95
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 96..150
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 72..94
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 123..146
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..183
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 338 AA; 35717 MW; 78EB338643C87D81 CRC64;
MAHEMMGGFF GHPPPPPATA AVGEEEDEVV EETEEGGHGG GVQGKLCARG HWRPAEDAKL
KDLVAQYGPQ NWNLIAEKLD GRSGKSCRLR WFNQLDPRIN RRAFTEEEEE RLMAAHRAYG
NKWALIARLF PGRTDNAVKN HWHVLMARRH REQSGAFRRR KPSSSSASPA PAPAPPPPPQ
PVVALHHHHH RYSQQYSGYS GAAESDESAS TCTTDLSLSS GSAAAAAAAA AAANIPCCFY
QSTPRASSSS TAACRAPRVA AAADTVAFFP GAGYDFAAAP HAMAPAAAST FAPSARSAFS
APAGRGEPPG AVDQRGGAQA TTDSHTIPFF DFLGVGAT
