CSC10_HUMAN
ID CSC10_HUMAN Reviewed; 136 AA.
AC Q5T4H9; A1L4M3;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Putative uncharacterized protein encoded by MIR1915-HG {ECO:0000305};
DE AltName: Full=Cancer susceptibility 10 protein {ECO:0000312|HGNC:HGNC:31448};
DE AltName: Full=Cancer susceptibility candidate gene 10 protein {ECO:0000312|HGNC:HGNC:31448};
DE AltName: Full=MIR1915 host gene protein {ECO:0000312|HGNC:HGNC:31448};
GN Name=MIR1915HG {ECO:0000312|HGNC:HGNC:31448};
GN Synonyms=C10orf114 {ECO:0000312|HGNC:HGNC:31448},
GN CASC10 {ECO:0000312|HGNC:HGNC:31448};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164054; DOI=10.1038/nature02462;
RA Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y.,
RA Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P.,
RA Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N.,
RA Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A.,
RA Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C.,
RA Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D.,
RA Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C.,
RA Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K.,
RA Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A.,
RA Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S.,
RA McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S.,
RA Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V.,
RA Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A.,
RA Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A.,
RA Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P.,
RA Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y.,
RA Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D.,
RA Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT "The DNA sequence and comparative analysis of human chromosome 10.";
RL Nature 429:375-381(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- CAUTION: Product of a dubious CDS prediction. May be a non-coding RNA.
CC {ECO:0000305}.
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DR EMBL; AL358780; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC130594; AAI30595.1; -; mRNA.
DR EMBL; BC132974; AAI32975.1; -; mRNA.
DR RefSeq; NP_001010911.1; NM_001010911.2.
DR AlphaFoldDB; Q5T4H9; -.
DR BioGRID; 134397; 2.
DR STRING; 9606.ENSP00000366317; -.
DR iPTMnet; Q5T4H9; -.
DR PhosphoSitePlus; Q5T4H9; -.
DR BioMuta; CASC10; -.
DR PaxDb; Q5T4H9; -.
DR PRIDE; Q5T4H9; -.
DR UCSC; uc001iqn.5; human.
DR GeneCards; MIR1915HG; -.
DR HGNC; HGNC:31448; MIR1915HG.
DR neXtProt; NX_Q5T4H9; -.
DR eggNOG; ENOG502TD4P; Eukaryota.
DR HOGENOM; CLU_156282_0_0_1; -.
DR InParanoid; Q5T4H9; -.
DR OrthoDB; 1296730at2759; -.
DR PhylomeDB; Q5T4H9; -.
DR TreeFam; TF353352; -.
DR PathwayCommons; Q5T4H9; -.
DR BioGRID-ORCS; 399726; 15 hits in 1056 CRISPR screens.
DR GenomeRNAi; 399726; -.
DR Pharos; Q5T4H9; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q5T4H9; protein.
DR Genevisible; Q5T4H9; HS.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..136
FT /note="Putative uncharacterized protein encoded by MIR1915-
FT HG"
FT /id="PRO_0000247126"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 73
FT /note="R -> P (in dbSNP:rs11012724)"
FT /id="VAR_033739"
SQ SEQUENCE 136 AA; 14851 MW; 09A8B4E3977DF9FC CRC64;
MQSREPSGWR TAERRRGWRC RGVPTPSGDR GPGAARPAAR GGAGETTGQQ RPLQVPGASA
AAARTRLLRW HHRVPSPRAT RSPGSIRRTS PCSGGPDRPE RPECADACCY LLDPFTLPLI
QDFFRGCAAS DFDRRD
