2SS_TAROF
ID 2SS_TAROF Reviewed; 44 AA.
AC P86783;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 1.
DT 25-MAY-2022, entry version 12.
DE RecName: Full=2S seed storage albumin protein {ECO:0000305};
DE AltName: Full=2S albumin {ECO:0000303|PubMed:19594427};
DE AltName: Full=To-A1 {ECO:0000303|PubMed:19594427};
DE Contains:
DE RecName: Full=2S albumin small chain {ECO:0000303|PubMed:19594427};
DE Contains:
DE RecName: Full=2S albumin large chain {ECO:0000303|PubMed:19594427};
DE Flags: Fragments;
OS Taraxacum officinale (Common dandelion) (Leontodon taraxacum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Crepidinae; Taraxacum.
OX NCBI_TaxID=50225;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, FUNCTION, SUBUNIT, AND MASS SPECTROMETRY.
RC TISSUE=Seed {ECO:0000269|PubMed:19594427};
RX PubMed=19594427; DOI=10.2174/092986610790963591;
RA Odintsova T.I., Rogozhin E.A., Sklyar I.V., Musolyamov A.K.,
RA Kudryavtsev A.M., Pukhalsky V.A., Smirnov A.N., Grishin E.V., Egorov T.A.;
RT "Antifungal activity of storage 2S albumins from seeds of the invasive weed
RT dandelion Taraxacum officinale Wigg.";
RL Protein Pept. Lett. 17:522-529(2010).
CC -!- FUNCTION: This is a 2S seed storage protein. Has antifungal activity.
CC Inhibits spore germination in H.sativum (IC(50)=62.5 ug/ml) and P.betae
CC (IC(50)=62.5 ug/ml). Inhibits growth of H.sativum, V.albo-atrum and
CC P.infestans. {ECO:0000269|PubMed:19594427}.
CC -!- SUBUNIT: The mature protein consists of a small and a large chain
CC linked by 2 disulfide bonds. {ECO:0000250|UniProtKB:P01089,
CC ECO:0000269|PubMed:19594427}.
CC -!- MASS SPECTROMETRY: [2S albumin small chain]: Mass=9631; Method=MALDI;
CC Note=Small chain.; Evidence={ECO:0000269|PubMed:19594427};
CC -!- MASS SPECTROMETRY: [2S albumin large chain]: Mass=4368; Method=MALDI;
CC Note=Large chain.; Evidence={ECO:0000269|PubMed:19594427};
CC -!- SIMILARITY: Belongs to the 2S seed storage albumins family.
CC {ECO:0000255}.
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DR AlphaFoldDB; P86783; -.
DR SMR; P86783; -.
DR GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR GO; GO:0050832; P:defense response to fungus; IDA:UniProtKB.
DR GO; GO:0002229; P:defense response to oomycetes; IDA:UniProtKB.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR SUPFAM; SSF47699; SSF47699; 1.
PE 1: Evidence at protein level;
KW Antimicrobial; Direct protein sequencing; Disulfide bond; Fungicide;
KW Seed storage protein; Storage protein.
FT CHAIN 1..>19
FT /note="2S albumin small chain"
FT /evidence="ECO:0000269|PubMed:19594427"
FT /id="PRO_0000399754"
FT CHAIN 20..>44
FT /note="2S albumin large chain"
FT /evidence="ECO:0000269|PubMed:19594427"
FT /id="PRO_0000399755"
FT DISULFID 7..42
FT /note="Interchain (between small and large chains)"
FT /evidence="ECO:0000250|UniProtKB:P01089"
FT DISULFID 19..31
FT /note="Interchain (between small and large chains)"
FT /evidence="ECO:0000250|UniProtKB:P01089"
FT DISULFID 32..?
FT /evidence="ECO:0000250|UniProtKB:P01089"
FT NON_CONS 19..20
FT /evidence="ECO:0000303|PubMed:19594427"
FT NON_TER 44
FT /evidence="ECO:0000303|PubMed:19594427"
SQ SEQUENCE 44 AA; 5163 MW; 730E4683FCB0E02D CRC64;
PVSRQQCSQR IQGERFNQCR SQMQDGQLQS CCQELQNVEE QCQC
