ID   CSDE_ECO57              Reviewed;         147 AA.
AC   P0AGF3; Q46926;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Sulfur acceptor protein CsdE;
GN   Name=csdE; Synonyms=ygdK; OrderedLocusNames=Z4128, ECs3671;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Stimulates the cysteine desulfurase activity of CsdA.
CC       Contains a cysteine residue (Cys-61) that acts to accept sulfur
CC       liberated via the desulfurase activity of CsdA. May be able to transfer
CC       sulfur to TcdA/CsdL. Seems to support the function of TcdA in the
CC       generation of cyclic threonylcarbamoyladenosine at position 37
CC       (ct(6)A37) in tRNAs that read codons beginning with adenine. Does not
CC       appear to participate in Fe/S biogenesis (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SufE family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG57925.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37094.1; -; Genomic_DNA.
DR   PIR; A85933; A85933.
DR   PIR; G91087; G91087.
DR   RefSeq; NP_311698.1; NC_002695.1.
DR   RefSeq; WP_000184261.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AGF3; -.
DR   BMRB; P0AGF3; -.
DR   SMR; P0AGF3; -.
DR   STRING; 155864.EDL933_3992; -.
DR   EnsemblBacteria; AAG57925; AAG57925; Z4128.
DR   EnsemblBacteria; BAB37094; BAB37094; ECs_3671.
DR   GeneID; 916526; -.
DR   KEGG; ece:Z4128; -.
DR   KEGG; ecs:ECs_3671; -.
DR   PATRIC; fig|386585.9.peg.3837; -.
DR   eggNOG; COG2166; Bacteria.
DR   HOGENOM; CLU_124502_1_0_6; -.
DR   OMA; HYFLADS; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   InterPro; IPR017763; Cysteine_desulfurase_CsdE.
DR   InterPro; IPR003808; Fe-S_metab-assoc_dom.
DR   PANTHER; PTHR43597; PTHR43597; 1.
DR   Pfam; PF02657; SufE; 1.
DR   TIGRFAMs; TIGR03391; FeS_syn_CsdE; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..147
FT                   /note="Sulfur acceptor protein CsdE"
FT                   /id="PRO_0000202137"
FT   ACT_SITE        61
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   147 AA;  15940 MW;  EECAB64427D42C41 CRC64;
     MTNPQFAGHP FGTTVTAETL RNTFAPLTQW EDKYRQLIML GKQLPALPDE LKAQAKEIAG
     CENRVWLGYT VAENGKMHFF GDSEGRIVRG LLAVLLTAVE GKTAAELQAQ SPLALFDELG
     LRAQLSASRS QGLNALSEAI IAATKQV