ID   CSEA_STRAW              Reviewed;         217 AA.
AC   Q82EB0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Lipoprotein CseA;
DE   Flags: Precursor;
GN   Name=cseA; OrderedLocusNames=SAV_4705;
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   -!- FUNCTION: May be involved in the stabilization of the cell envelope or
CC       may interact with the sensor protein CseC to modulate its activity, in
CC       response to cell envelope stress. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC72417.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000030; BAC72417.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_037652360.1; NZ_JZJK01000054.1.
DR   AlphaFoldDB; Q82EB0; -.
DR   STRING; 227882.SAV_4705; -.
DR   EnsemblBacteria; BAC72417; BAC72417; SAVERM_4705.
DR   KEGG; sma:SAVERM_4705; -.
DR   eggNOG; ENOG502ZWYH; Bacteria.
DR   HOGENOM; CLU_078792_0_0_11; -.
DR   OMA; KRELKPC; -.
DR   OrthoDB; 1673581at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           35..217
FT                   /note="Lipoprotein CseA"
FT                   /id="PRO_0000314478"
FT   REGION          39..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          192..217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           35
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           35
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   217 AA;  22396 MW;  DCA79EFD36DDFCEE CRC64;
     MRGLGTESLR ARGALKAAIA AVAGLAVLGL SVSACGTGGT GARDEGPAGS DSVAAGAATP
     TVSPSKAPKS VDAVKLVKDD PKVGAAVKRA LKPCVADEYP VDVSYGDLTG GSADDIVVNV
     MTCGDAVGIG SYVYREQGHS YENVFRAEEP PVYAEIDRGE LVVTQQMYEK DDPVSYPSSE
     EVITYSWSAN RFSEESRTHT EYSNAVGGTD SATPAPN